Progressive apraxia of speech as a sign of motor neuron disease

Joseph R. Duffy, Richard K. Peach, Edythe A. Strand

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Purpose: To document and describe in detail the occurrence of apraxia of speech (AOS) in a group of individuals with a diagnosis of motor neuron disease (MND). Method: Seven individuals with MND and AOS were identified from among 80 patients with a variety of neurodegenerative diseases and AOS (J. R. Duffy, 2006). The history, presenting complaints, neurological findings, and speech-language findings were documented for each case. Results: Spastic or mixed spastic-flaccid dysarthria was present in all 7 cases. The AOS was judged as worse than the dysarthria in 4 cases. Nonverbal oral apraxia was eventually present in all cases. Aphasia was present in 2 cases and equivocally present in another 2. Dementia was present in 1 case and equivocally present in 2. Conclusions: AOS can occur in MND, typically also with dysarthria, but not invariably with aphasia or other cognitive deficits. Thus, a diagnosis of MND does not preclude the presence of AOS. More importantly, MND should be a diagnostic consideration when AOS is a prominent sign of degenerative disease.

Original languageEnglish (US)
Pages (from-to)198-208
Number of pages11
JournalAmerican Journal of Speech-Language Pathology
Volume16
Issue number3
DOIs
StatePublished - Aug 2007

Fingerprint

Apraxias
Motor Neuron Disease
Disease
Dysarthria
physical disability
Aphasia
speech disorder
Muscle Spasticity
present
dementia
complaint
Neurodegenerative Diseases
Dementia
diagnostic
deficit
Language
History

Keywords

  • Amyotrophic lateral sclerosis
  • Apraxia of speech
  • Motor neuron disease

ASJC Scopus subject areas

  • Rehabilitation
  • Linguistics and Language
  • Health Professions(all)

Cite this

Progressive apraxia of speech as a sign of motor neuron disease. / Duffy, Joseph R.; Peach, Richard K.; Strand, Edythe A.

In: American Journal of Speech-Language Pathology, Vol. 16, No. 3, 08.2007, p. 198-208.

Research output: Contribution to journalArticle

Duffy, Joseph R. ; Peach, Richard K. ; Strand, Edythe A. / Progressive apraxia of speech as a sign of motor neuron disease. In: American Journal of Speech-Language Pathology. 2007 ; Vol. 16, No. 3. pp. 198-208.
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