Progress on new vaccine strategies for the immunotherapy and prevention of cancer

Jay A. Berzofsky, Masaki Terabe, SangKon Oh, Igor M. Belyakov, Jeffrey D. Ahlers, John E. Janik, John C. Morris

Research output: Contribution to journalReview article

217 Scopus citations

Abstract

In recent years, great strides in understanding and regulating the immune system have led to new hope for harnessing its exquisite specificity to destroy cancer cells without affecting normal tissues. This review examines the fundamental immunologic advances and the novel vaccine strategies arising from these advances, as well as the early clinical trials studying new approaches to treat or prevent cancer.

Original languageEnglish (US)
Pages (from-to)1515-1525
Number of pages11
JournalJournal of Clinical Investigation
Volume113
Issue number11
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Berzofsky, J. A., Terabe, M., Oh, S., Belyakov, I. M., Ahlers, J. D., Janik, J. E., & Morris, J. C. (2004). Progress on new vaccine strategies for the immunotherapy and prevention of cancer. Journal of Clinical Investigation, 113(11), 1515-1525. https://doi.org/10.1172/JCI21926