Progress in the understanding of polycystic kidney disease

Research output: Contribution to journalArticle

Abstract

The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.

Original languageEnglish (US)
JournalNature Reviews Nephrology
DOIs
StateAccepted/In press - Jan 1 2019

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TRPP Cation Channels
Autosomal Dominant Polycystic Kidney
Polycystic Kidney Diseases
Genetic Structures
GTP-Binding Proteins
Immune System
Proteins

ASJC Scopus subject areas

  • Nephrology

Cite this

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title = "Progress in the understanding of polycystic kidney disease",
abstract = "The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.",
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