Abstract
The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.
| Original language | English (US) |
|---|---|
| Journal | Nature Reviews Nephrology |
| DOIs | |
| State | Accepted/In press - Jan 1 2019 |
Fingerprint
ASJC Scopus subject areas
- Nephrology
Cite this
Progress in the understanding of polycystic kidney disease. / Torres, Vicente; Harris, Peter C.
In: Nature Reviews Nephrology, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Progress in the understanding of polycystic kidney disease
AU - Torres, Vicente
AU - Harris, Peter C
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.
AB - The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.
UR - http://www.scopus.com/inward/record.url?scp=85059544005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85059544005&partnerID=8YFLogxK
U2 - 10.1038/s41581-018-0108-1
DO - 10.1038/s41581-018-0108-1
M3 - Article
C2 - 30607031
AN - SCOPUS:85059544005
JO - Nature Reviews Nephrology
JF - Nature Reviews Nephrology
SN - 1759-507X
ER -