Progress and Challenges in Survivorship After Acute Myeloid Leukemia in Adults

Ginna Granroth, Nandita Khera, Cecilia Arana Yi

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: Acute myeloid leukemia (AML) survivors face unique challenges affecting long-term outcomes and quality of life. There is scant literature on the long-term impact of AML treatment in physical and mental health, disease recurrence, and financial burden in survivors. Recent Findings: Fatigue, mental health concerns, infections, sexual dysfunction, and increase cancer recurrence occur after AML treatment. Chronic graft-versus-host disease (GVHD) and infections are common concerns in AML after hematopoietic stem cell transplantation (HCT). Survivorship guidelines encompass symptoms and complications but fail to provide an individualized care plan for AML survivors. Studies in patient-reported outcomes (PROs) and health-related quality of life (HRQoL) are sparse. Summary: Here we discuss the most common aspects pertaining to AML survivorship, late complications, care delivery, prevention of disease recurrence, and potential areas for implementation.

Original languageEnglish (US)
JournalCurrent Hematologic Malignancy Reports
DOIs
StateAccepted/In press - 2022

Keywords

  • Allo-HCT
  • Financial burden
  • HRQoL
  • MRD
  • PRO
  • Survivorship care plan
  • Survivorship clinic

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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