TY - JOUR
T1 - Programmed cell death
T2 - Alive and well in the new millennium
AU - Kaufmann, Scott H.
AU - Hengartner, Michael O.
N1 - Funding Information:
Research in the authors’ laboratories is supported by grants from the National Cancer Institute, the National Institute of General Medical Sciences, the Department of Defense Breast Cancer Program, the Swiss National Science Foundation, and the Ernst Hadorn Foundation. We thank Bill Earnshaw, Yuri Lazebnik, David Vaux and members of our laboratories for stimulating suggestions. We also apologize to the many authors whose work could not be cited here because of space limitations.
PY - 2001/12/1
Y1 - 2001/12/1
N2 - Research performed over the past decade has transformed apoptosis from a distinctive form of cell death known only by its characteristic morphology and genomic destruction to an increasingly well understood cellular disassembly pathway remarkable for its complex and multifaceted regulation. Here, we summarize current understanding of apoptotic events, note recent advances in this field and identify questions that might help guide research in the coming years.
AB - Research performed over the past decade has transformed apoptosis from a distinctive form of cell death known only by its characteristic morphology and genomic destruction to an increasingly well understood cellular disassembly pathway remarkable for its complex and multifaceted regulation. Here, we summarize current understanding of apoptotic events, note recent advances in this field and identify questions that might help guide research in the coming years.
UR - http://www.scopus.com/inward/record.url?scp=0035575679&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035575679&partnerID=8YFLogxK
U2 - 10.1016/S0962-8924(01)02173-0
DO - 10.1016/S0962-8924(01)02173-0
M3 - Review article
C2 - 11719060
AN - SCOPUS:0035575679
SN - 0962-8924
VL - 11
SP - 526
EP - 534
JO - Trends in Cell Biology
JF - Trends in Cell Biology
IS - 12
ER -