Prognostic importance of diastolic function and filling pressure in patients with acute myocardial infarction

Jacob E. Møller, Patricia A. Pellikka, Graham S. Hillis, Jae K. Oh

Research output: Contribution to journalReview article

125 Scopus citations

Abstract

Doppler echocardiographic assessment of hemodynamics in the acute setting of AMI provides independent noninvasive prognostic information. This is particularly true in the subgroup of patients who have evidence of elevated LV filling pressures despite relatively preserved systolic function. Although ventricular remodeling and hyperactivity of the renin-angiotensin-aldosterone system most likely contribute to the excess mortality in these patients, further work is required to increase our understanding of the pathophysiology. As our knowledge expands, it is likely that this will lead to new opportunities to modify the excess risk and improve patient outcome.

Original languageEnglish (US)
Pages (from-to)438-444
Number of pages7
JournalCirculation
Volume114
Issue number5
DOIs
StatePublished - Aug 1 2006

Keywords

  • Diastole
  • Echocardiography
  • Heart diseases
  • Ischemia
  • Myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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