@article{f84bd16ea62b4e58a459f3ee8bee2f53,
title = "Proceedings of the Canadian Frailty Network Workshop: Identifying Biomarkers of Frailty to Support Frailty Risk Assessment, Diagnosis and Prognosis. Toronto, January 15, 2018",
abstract = "The Canadian Frailty Network (CFN), a pan-Canadian not-for-profit organization funded by the Government of Canada through the Networks of Centres of Excellence Program, is dedicated to improving the care of older Canadians living with frailty. The CFN has partnered with the Canadian Longitudinal Study on Aging (CLSA) to measure potential frailty biomarkers in biological samples (whole blood, plasma, urine) collected in over 30,000 CLSA participants. CFN hosted a workshop in Toronto on January 15 2018, bringing together experts in the field of biomarkers, aging and frailty. The overall objectives of the workshop were to start building a consensus on potential frailty biomarker domains and identify specific frailty biomarkers to be measured in the CLSA biological samples. The workshop was structured with presentations in the morning to frame the discussions for the afternoon session, which was organized as a free-flowing discussion to benefit from the expertise of the participants. Participants and speakers were from Canada, Italy, Spain, United Kingdom and the United States. Herein we provide pertinent background information, a summary of all the presentations with key figures and tables, and the distillation of the discussions. In addition, moving forward, the principles CFN will use to approach frailty biomarker research and development are outlined. Findings from the workshop are helping CFN and CLSA plan and conduct the analysis of biomarkers in the CLSA samples and which will inform a follow-up data access competition.",
keywords = "CFN, CLSA, aging, biomarkers, frailty, frailty index, older adults, seniors",
author = "{Canadian Frailty Network} and John Muscedere and Kim, {P. M.} and J. Afilalo and C. Balion and Baracos, {V. E.} and D. Bowdish and M. Cesari and Erusalimsky, {J. D.} and T. F{\"u}l{\"o}p and G. Heckman and Howlett, {S. E.} and Khadaroo, {R. G.} and Kirkland, {J. L.} and {Rodriguez Ma{\~n}as}, L. and E. Marzetti and G. Par{\'e} and P. Raina and K. Rockwood and A. Sinclair and C. Skappak and C. Verschoor and S. Walter",
note = "Funding Information: Conflict of interest disclosures: Matteo Cesari, Emanuele Marzetti and Leocadio Rodriguez Ma{\~n}as are partners of the SPRINTT consortium, which is partly funded by the European Federation of Pharmaceutical Industries and Associations (EFPIA). Kenneth Rockwood is President and Chief Science Officer of DGI Clinical, which in the last five years has contracts with pharma and device manufacturers (Baxter, Baxalta, Shire, Hollister, Nutricia, Roche, Otsuka) on individualized outcome measurement. In 2017 he attended an advisory board meeting with Lundbeck. He is Associate Director of the Canadian Consortium on Neurodegeneration in Aging, which is funded by the Canadian Institutes of Health Research, and with additional funding from the Alzheimer Society of Canada and several other charities, as well as, in first phase (2013–2018), from Pfizer Canada and Sanofi Canada. He receives career support from the Dalhousie Medical Research Foundation as the Kathryn Allen Weldon Professor of Alzheimer Research, and research support from the Canadian Institutes of Health Research, the Nova Scotia Health Research Foundation, the Capital Health Research Fund and the Fountain Family Innovation Fund of the Nova Scotia Health Authority Foundation. Acknowledgements Funding Information: The Canadian Frailty Network (CFN) is a pan-Canadian network focused on the care of older citizens living with frailty. CFN is comprised of nearly 3,500 corporate and nonprofit partners, researchers, scientists, health-care professionals, citizens, students, trainees, educators, and decision-makers. CFN supports and catalyzes original research and innovations to improve the care and quality of life of Canadians living with frailty across all settings of care. The Network also trains the next generation of health-care professionals and scientists. CFN is funded by the Government of Canada through the Networks of Centres of Excellence (NCE) Program. In early 2017, in recognition of the work done in its first five years of operation, the Government of Canada announced funding for a second five-term (2017–2022). Publisher Copyright: {\textcopyright} 2019, Serdi and Springer Nature Switzerland AG.",
year = "2019",
month = jul,
doi = "10.14283/jfa.2019.12",
language = "English (US)",
volume = "8",
pages = "106--116",
journal = "The Journal of frailty & aging",
issn = "2260-1341",
publisher = "Serdi Publishing Company",
number = "3",
}