TY - JOUR
T1 - Probiotics and irritable bowel syndrome
T2 - rationale, mechanisms, and efficacy.
AU - Camilleri, Michael
PY - 2008
Y1 - 2008
N2 - To review the rationale and current evidence for the efficacy of probiotics in the treatment of irritable bowel syndrome (IBS), the following specific questions are addressed from a review of the published literature: Are bacterial flora altered in IBS? Is infection a significant risk factor for IBS? How prominent is the inflammation in IBS? Do probiotics change bacterial flora? Do probiotics adhere to mucosa? What are the potential mechanisms of action of probiotics in IBS: immune function, motor, secretory, sensory, and fermentation? What is the efficacy of probiotics in IBS?
AB - To review the rationale and current evidence for the efficacy of probiotics in the treatment of irritable bowel syndrome (IBS), the following specific questions are addressed from a review of the published literature: Are bacterial flora altered in IBS? Is infection a significant risk factor for IBS? How prominent is the inflammation in IBS? Do probiotics change bacterial flora? Do probiotics adhere to mucosa? What are the potential mechanisms of action of probiotics in IBS: immune function, motor, secretory, sensory, and fermentation? What is the efficacy of probiotics in IBS?
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M3 - Review article
C2 - 18806702
AN - SCOPUS:58149105515
SN - 0192-0790
VL - 42 Suppl 3 Pt 1
SP - S123-125
JO - Journal of clinical gastroenterology
JF - Journal of clinical gastroenterology
ER -