Probable adult polyglucosan body disease

Caroline M. Klein, E. Peter Bosch, Peter J. Dyck

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Adult polyglucosan body disease is a clinicopathologic entity characterized by progressive upper and lower motor neuron dysfunction, sensory loss in the lower extremities, sphincter dysfunction, and occasionally dementia. Pathologically, numerous large polyglucosan bodies are noted in peripheral nerves, cerebral hemispheres, and the spinal cord, as well as in other systemic tissues. We present a case of probable adult polyglucosan body disease based on clinical history and examination, magnetic resonance images, and sural nerve biopsy findings.

Original languageEnglish (US)
Pages (from-to)1327-1331
Number of pages5
JournalMayo Clinic proceedings
Volume75
Issue number12
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Medicine(all)

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