Principles of chemotherapy

Grace K. Dy, Alex Adjei

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Abstract

During World War II, sailors who were accidentally exposed to nitrogen mustard following the explosion of a ship developed marrow and lymphoid hypoplasia. 1 This serendipitous discovery led to the first clinical trial conducted in 1942 using nitrogen mustard in patients with malignant lymphomas at Yale University.2 This marked the beginning of a new era of research in the quest for effective and safe drugs used in cancer chemotherapy.

Original languageEnglish (US)
Title of host publicationOncology
Subtitle of host publicationAn Evidence-Based Approach
PublisherSpringer New York
Pages14-40
Number of pages27
ISBN (Print)0387242910, 9780387242910
DOIs
StatePublished - Dec 1 2006

Fingerprint

Mechlorethamine
Drug Therapy
World War II
Ships
Explosions
Lymphoma
Bone Marrow
Clinical Trials
Research
Pharmaceutical Preparations
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dy, G. K., & Adjei, A. (2006). Principles of chemotherapy. In Oncology: An Evidence-Based Approach (pp. 14-40). Springer New York. https://doi.org/10.1007/0-387-31056-8_2

Principles of chemotherapy. / Dy, Grace K.; Adjei, Alex.

Oncology: An Evidence-Based Approach. Springer New York, 2006. p. 14-40.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dy, GK & Adjei, A 2006, Principles of chemotherapy. in Oncology: An Evidence-Based Approach. Springer New York, pp. 14-40. https://doi.org/10.1007/0-387-31056-8_2
Dy GK, Adjei A. Principles of chemotherapy. In Oncology: An Evidence-Based Approach. Springer New York. 2006. p. 14-40 https://doi.org/10.1007/0-387-31056-8_2
Dy, Grace K. ; Adjei, Alex. / Principles of chemotherapy. Oncology: An Evidence-Based Approach. Springer New York, 2006. pp. 14-40
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