Primer on medical genomics. Part I: History of genetics and sequencing of the human genome

Cindy Pham Lorentz, Eric D. Wieben, Ayalew Tefferi, David A.H. Whiteman, Gordon W. Dewald

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

In comparison with most other disciplines of science, the field of genetics is still in its youth. The majority of scientific work in genetics has been done in the past 150 years. The successful preliminary sequencing of the human genome was announced in 2001. Nonetheless, interest in heredity and in other concepts within the field of genetics has existed since the beginning of humanity. This article provides an account of the history of genetics, spanning from humankind's initial attempts to understand and influence heredity, to the early scientific work in the field of genetics, and subsequently to the advancements in modern genetics. Additionally, the Human Genome Project is summarized, from inception to publication of the "first draft" of the human genome sequence.

Original languageEnglish (US)
Article number62022
Pages (from-to)773-782
Number of pages10
JournalMayo Clinic proceedings
Volume77
Issue number8
DOIs
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Medicine(all)

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