Primary sclerosing cholangitis

Evolving concepts in diagnosis and treatment

Denise Harnois, Keith D. Lindor

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Primary sclerosing cholangitis is an increasingly recognized cause of chronic cholestatic liver disease. The etiology is unknown, although a number of immunologic and nonimmunologic factors have been considered. The most important diagnostic findings are diffuse irregularity and narrowing of extrahepatic and intrahepatic bile ducts. The prognosis varies, and a number of relatively unique complications may develop. No adequate treatment exists, although a number of potential treatments have been evaluated. Liver transplantation still remains the most appropriate treatment for end-stage disease. These various topics related to primary sclerosing cholangitis are reviewed.

Original languageEnglish (US)
Pages (from-to)23-41
Number of pages19
JournalDigestive Diseases
Volume15
Issue number1-2
DOIs
StatePublished - Jan 1 1997

Fingerprint

Sclerosing Cholangitis
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Immunologic Factors
Liver Transplantation
Liver Diseases
Therapeutics

Keywords

  • Diagnosis
  • Management
  • Primary sclerosing cholangitis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Primary sclerosing cholangitis : Evolving concepts in diagnosis and treatment. / Harnois, Denise; Lindor, Keith D.

In: Digestive Diseases, Vol. 15, No. 1-2, 01.01.1997, p. 23-41.

Research output: Contribution to journalArticle

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