Primary prophylaxis of variceal bleeding

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Primary prevention of variceal bleeding is an important and long-debated topic in the management of patients with cirrhosis and esophageal varices. Prophylaxis is recommended for high-risk patients with small esophageal varices (advanced liver disease and/or presence of red wale marks) and those with medium/large varices. Nonselective β-blockers and endoscopic band ligation have been shown to be equally effective in primary prevention of variceal bleeding and are the only currently recommended therapies. Controversy still exists, however, regarding which one of these strategies is preferred. This article reviews the established recommendations and recent advances in the prevention of first esophageal variceal bleeding.

Original languageEnglish (US)
Pages (from-to)335-345
Number of pages11
JournalClinics in Liver Disease
Volume18
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Esophageal and Gastric Varices
Primary Prevention
Hemorrhage
Wales
Varicose Veins
Ligation
Liver Diseases
Fibrosis
Therapeutics

Keywords

  • Cirrhosis
  • Endoscopy
  • Gastrointestinal hemorrhage
  • Portal hypertension
  • β-blockers

ASJC Scopus subject areas

  • Hepatology
  • Medicine(all)

Cite this

Primary prophylaxis of variceal bleeding. / Simonetto, Douglas; Shah, Vijay; Kamath, Patrick Sequeira.

In: Clinics in Liver Disease, Vol. 18, No. 2, 2014, p. 335-345.

Research output: Contribution to journalArticle

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