Abstract
Mucinous cystic neoplasms (MCNs) of the pancreas represent one of the most common primary pancreatic cystic neoplasms, accounting for approximately half of these cases. MCNs are observed almost exclusively in women, and most commonly are located in the body/tail of the pancreas. In contrast to SCNs, MCNs have malignant potential. Proliferative changes (hyperplasia with or without atypia, borderline changes, non-invasive or carcinomas in-situ, and invasive carcinomas) can often be observed within the same neoplasm. Several risk factors for the presence of underlying malignancy within an MCN have recently been recognized. Cross-sectional imaging is of key importance for the diagnostic evaluation of patients with a cystic pancreatic lesion. Cyst fluid examination (cytology, biochemical/genetic analysis) is possible by using fine needle aspiration of the MCN, usually under endoscopic guidance, and may provide useful information for the differential diagnosis. Since MCNs have malignant potential, surgical resection is the treatment of choice.
| Original language | English (US) |
|---|---|
| Journal | Surgical Oncology |
| Volume | 20 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 2011 |
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Keywords
- Cystic neoplasms of the pancreas
- Endoscopic ultrasonography
- Intraductal papillary mucinous neoplasm
- Mucinous cystadenocarcinoma
- Mucinous cystadenoma
- Mucinous cystic neoplasm
- Serous cystic neoplasm
ASJC Scopus subject areas
- Oncology
- Surgery
Cite this
Primary pancreatic cystic neoplasms revisited : Part II. Mucinous cystic neoplasms. / Sakorafas, George H.; Smyrniotis, Vasileios; Reid-Lombardo, Kaye M.; Sarr, Michael G.
In: Surgical Oncology, Vol. 20, No. 2, 06.2011.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Primary pancreatic cystic neoplasms revisited
T2 - Part II. Mucinous cystic neoplasms
AU - Sakorafas, George H.
AU - Smyrniotis, Vasileios
AU - Reid-Lombardo, Kaye M.
AU - Sarr, Michael G.
PY - 2011/6
Y1 - 2011/6
N2 - Mucinous cystic neoplasms (MCNs) of the pancreas represent one of the most common primary pancreatic cystic neoplasms, accounting for approximately half of these cases. MCNs are observed almost exclusively in women, and most commonly are located in the body/tail of the pancreas. In contrast to SCNs, MCNs have malignant potential. Proliferative changes (hyperplasia with or without atypia, borderline changes, non-invasive or carcinomas in-situ, and invasive carcinomas) can often be observed within the same neoplasm. Several risk factors for the presence of underlying malignancy within an MCN have recently been recognized. Cross-sectional imaging is of key importance for the diagnostic evaluation of patients with a cystic pancreatic lesion. Cyst fluid examination (cytology, biochemical/genetic analysis) is possible by using fine needle aspiration of the MCN, usually under endoscopic guidance, and may provide useful information for the differential diagnosis. Since MCNs have malignant potential, surgical resection is the treatment of choice.
AB - Mucinous cystic neoplasms (MCNs) of the pancreas represent one of the most common primary pancreatic cystic neoplasms, accounting for approximately half of these cases. MCNs are observed almost exclusively in women, and most commonly are located in the body/tail of the pancreas. In contrast to SCNs, MCNs have malignant potential. Proliferative changes (hyperplasia with or without atypia, borderline changes, non-invasive or carcinomas in-situ, and invasive carcinomas) can often be observed within the same neoplasm. Several risk factors for the presence of underlying malignancy within an MCN have recently been recognized. Cross-sectional imaging is of key importance for the diagnostic evaluation of patients with a cystic pancreatic lesion. Cyst fluid examination (cytology, biochemical/genetic analysis) is possible by using fine needle aspiration of the MCN, usually under endoscopic guidance, and may provide useful information for the differential diagnosis. Since MCNs have malignant potential, surgical resection is the treatment of choice.
KW - Cystic neoplasms of the pancreas
KW - Endoscopic ultrasonography
KW - Intraductal papillary mucinous neoplasm
KW - Mucinous cystadenocarcinoma
KW - Mucinous cystadenoma
KW - Mucinous cystic neoplasm
KW - Serous cystic neoplasm
UR - http://www.scopus.com/inward/record.url?scp=79954572226&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79954572226&partnerID=8YFLogxK
U2 - 10.1016/j.suronc.2010.12.003
DO - 10.1016/j.suronc.2010.12.003
M3 - Article
C2 - 21251815
AN - SCOPUS:79954572226
VL - 20
JO - Surgical Oncology
JF - Surgical Oncology
SN - 0960-7404
IS - 2
ER -