Primary pancreatic cystic neoplasms revisited. Part I: Serous cystic neoplasms

George H. Sakorafas, Vasileios Smyrniotis, Kaye M. Reid-Lombardo, Michael G. Sarr

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations

Abstract

Primary pancreatic cystic neoplasms have been recognized increasingly during the two recent decades and include mainly serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. Serous cystic neoplasms represent about 30% of all cystic neoplasms of the pancreas and are characterized by their microcystic appearance (on imaging, macroscopically, and microscopically) and their benign biologic behavior. Modern diagnostic methodology allows the preoperative diagnosis with an acceptable accuracy. Currently, indications for resection of serous cystic neoplasms of the pancreas include the presence of symptoms, size > 4 cm (because these 'large' neoplasms have a more rapid growth rate and probably will soon become symptomatic), and any uncertainty about the diagnosis of a serous versus a mucinous cystic neoplasm. Resection should also be considered for lesions in the body/tail of the pancreas. Conservative treatment is a reasonable option in selected patients (for example in the presence of small, asymptomatic lesions in the pancreatic head, especially in the frail or elderly patient).

Original languageEnglish (US)
Pages (from-to)e84-e92
JournalSurgical Oncology
Volume20
Issue number2
DOIs
StatePublished - Jun 1 2011

Keywords

  • Cystic neoplasm of the pancreas
  • Intraductal papillary mucinous neoplasm
  • Mucinous cystic neoplasm
  • Serous cystadenocarcinoma
  • Serous cystadenoma

ASJC Scopus subject areas

  • Surgery
  • Oncology

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