TY - JOUR
T1 - Primary pancreatic cystic neoplasms revisited. Part I
T2 - Serous cystic neoplasms
AU - Sakorafas, George H.
AU - Smyrniotis, Vasileios
AU - Reid-Lombardo, Kaye M.
AU - Sarr, Michael G.
PY - 2011/6
Y1 - 2011/6
N2 - Primary pancreatic cystic neoplasms have been recognized increasingly during the two recent decades and include mainly serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. Serous cystic neoplasms represent about 30% of all cystic neoplasms of the pancreas and are characterized by their microcystic appearance (on imaging, macroscopically, and microscopically) and their benign biologic behavior. Modern diagnostic methodology allows the preoperative diagnosis with an acceptable accuracy. Currently, indications for resection of serous cystic neoplasms of the pancreas include the presence of symptoms, size > 4 cm (because these 'large' neoplasms have a more rapid growth rate and probably will soon become symptomatic), and any uncertainty about the diagnosis of a serous versus a mucinous cystic neoplasm. Resection should also be considered for lesions in the body/tail of the pancreas. Conservative treatment is a reasonable option in selected patients (for example in the presence of small, asymptomatic lesions in the pancreatic head, especially in the frail or elderly patient).
AB - Primary pancreatic cystic neoplasms have been recognized increasingly during the two recent decades and include mainly serous cystic neoplasms, mucinous cystic neoplasms, and intraductal papillary mucinous neoplasms. Serous cystic neoplasms represent about 30% of all cystic neoplasms of the pancreas and are characterized by their microcystic appearance (on imaging, macroscopically, and microscopically) and their benign biologic behavior. Modern diagnostic methodology allows the preoperative diagnosis with an acceptable accuracy. Currently, indications for resection of serous cystic neoplasms of the pancreas include the presence of symptoms, size > 4 cm (because these 'large' neoplasms have a more rapid growth rate and probably will soon become symptomatic), and any uncertainty about the diagnosis of a serous versus a mucinous cystic neoplasm. Resection should also be considered for lesions in the body/tail of the pancreas. Conservative treatment is a reasonable option in selected patients (for example in the presence of small, asymptomatic lesions in the pancreatic head, especially in the frail or elderly patient).
KW - Cystic neoplasm of the pancreas
KW - Intraductal papillary mucinous neoplasm
KW - Mucinous cystic neoplasm
KW - Serous cystadenocarcinoma
KW - Serous cystadenoma
UR - http://www.scopus.com/inward/record.url?scp=79954587962&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79954587962&partnerID=8YFLogxK
U2 - 10.1016/j.suronc.2010.12.002
DO - 10.1016/j.suronc.2010.12.002
M3 - Review article
C2 - 21237638
AN - SCOPUS:79954587962
SN - 0960-7404
VL - 20
SP - e84-e92
JO - Surgical Oncology
JF - Surgical Oncology
IS - 2
ER -