Primary neuroendocrine tumors and primary neuroendocrine carcinomas of the liver: a proposal for a multidiscipline definition

Michael Torbenson, Sudhakar K Venkatesh, Thorvardur R. Halfdanarson, Patrick J. Navin, Patrick Sequeira Kamath, Lori Ann Erickson

Research output: Contribution to journalReview articlepeer-review

Abstract

Primary hepatic neuroendocrine tumors and primary hepatic neuroendocrine carcinomas are rare and pose challenges for both diagnosis and for determining whether the tumor is primary to the liver versus metastatic disease. The lack of a uniform definition for primary hepatic neuroendocrine neoplasms is also a limitation to understanding and treating these rare tumors. Recently, there have been significant histological advances in the diagnosis and classification of neuroendocrine tumors in general, as well as significant advances in imaging for neuroendocrine neoplasms, all of which are important for their treatment. This article presents a multiple disciplinary definition and proposed guidelines for diagnosing a neuroendocrine tumor/neuroendocrine carcinomas as being primary to the liver.

Original languageEnglish (US)
JournalHuman Pathology
DOIs
StateAccepted/In press - 2022

Keywords

  • Hepatocellular
  • Liver
  • Neuroendocrine carcinoma
  • Neuroendocrine tumor
  • Primary

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Primary neuroendocrine tumors and primary neuroendocrine carcinomas of the liver: a proposal for a multidiscipline definition'. Together they form a unique fingerprint.

Cite this