Primary lymph node presentation of angiocentric lymphoma associated with features of a hemophagocytic syndrome

Brian D. Kueck, Curtis A. Hanson, David E. Weissman, Katherine Bayliss

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The spectrum of post‐thymic T‐cell neoplasia includes the angiocentric immunoproliterative lesions, a group of disorders histologically exhibiting vascular infiltration and destruction; included among these disorders is angiocentric lymphoma. In contrast to the typical extranodal presentation seen in the angiocentric immunoproiiferative lesions, this report describes a case of angiocentric lymphoma presenting as primary lymph node disease with clinicopathologic findings mimicking a hemophagocytic syndrome. Rearrangement of the T‐cell receptor beta chain documents this case to be a clonal T‐cell neoplasm. The association of this distinct histologic type of T‐cell malignancy with hemophagocytic syndromes is reviewed.

Original languageEnglish (US)
Pages (from-to)104-111
Number of pages8
JournalAmerican journal of hematology
Volume30
Issue number2
DOIs
StatePublished - Feb 1989

Keywords

  • T‐cell lymphoma
  • erythrophagocytosis
  • histiocytic
  • hyperplasia
  • lymphatic vascuiitis

ASJC Scopus subject areas

  • Hematology

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