Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil

Steven Vernino, Diva R. Salomao, Thomas Matthew Habermann, Brian Patrick O'Neill

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Mycophenolate mofetil (MM), an immunosuppressant used after organ transplantation, is also used for treatment of autoimmune myasthenia gravis (MG). A patient with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment. Primary CNS lymphoma regressed on withdrawal of MM. Despite minimal short-term side effects and apparent efficacy, chronic treatment of MG with MM may be associated with increased risk of lymphoproliferative disorders.

Original languageEnglish (US)
Pages (from-to)639-641
Number of pages3
JournalNeurology
Volume65
Issue number4
DOIs
StatePublished - Aug 23 2005

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Mycophenolic Acid
Myasthenia Gravis
Lymphoma
Lymphoproliferative Disorders
Organ Transplantation
Therapeutics
Immunosuppressive Agents

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil. / Vernino, Steven; Salomao, Diva R.; Habermann, Thomas Matthew; O'Neill, Brian Patrick.

In: Neurology, Vol. 65, No. 4, 23.08.2005, p. 639-641.

Research output: Contribution to journalArticle

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