Primary angiomatoid fibrous histiocytoma of the lung with mediastinal lymph node metastasis

Chee Kiang Tay, Mariko Siyue Koh, Angela Takano, Marie Christine Aubry, William R. Sukov, Andrew L. Folpe

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Angiomatoid fibrous histiocytoma (AFH), a rare soft tissue tumor of borderline malignancy, typically occurs in the subcutis of the accessible soft tissues, most often in children and young adults. Lymph node and/or distant metastasis is seen in less than 2% of patients with AFH. Exceptionally rare examples of AFH have been reported in visceral locations, including the lung. We report a genetically confirmed primary pulmonary AFH in a 70-year-old woman with mediastinal lymph node metastasis, representing to the best of our knowledge the first report of metastases from a visceral AFH.

Original languageEnglish (US)
Pages (from-to)134-137
Number of pages4
JournalHuman Pathology
Volume58
DOIs
StatePublished - Dec 1 2016

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Keywords

  • Angiomatoid fibrous histiocytoma
  • EWSR1
  • Fluorescence in situ hybridization
  • Pulmonary neoplasms
  • Soft tissue neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Tay, C. K., Koh, M. S., Takano, A., Aubry, M. C., Sukov, W. R., & Folpe, A. L. (2016). Primary angiomatoid fibrous histiocytoma of the lung with mediastinal lymph node metastasis. Human Pathology, 58, 134-137. https://doi.org/10.1016/j.humpath.2016.07.022