Abstract
Peripheral neuropathy in primary (AL) amyloidosis is usually lower-limb predominant, length-dependent, symmetrical, and affects small (pain and autonomic) fibers, as much or more than large fibers. We report a patient with stepwise progressive, multiple upper limb mononeuropathies that were due to nerve biopsy-proven primary amyloidosis (lambda light chain), with no systemic or autonomic features. Recognition that light chain amyloidosis may be the cause of a multiple mononeuropathy pattern adds to the differential diagnosis of this clinical phenotype.
Original language | English (US) |
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Pages (from-to) | 710-715 |
Number of pages | 6 |
Journal | Muscle and Nerve |
Volume | 41 |
Issue number | 5 |
DOIs | |
State | Published - May 2010 |
Keywords
- Amyloid neuropathy
- Amyloidosis
- Mononeuritis multiplex
- Necrotizing vasculitis
- Nerve biopsy
ASJC Scopus subject areas
- Physiology
- Clinical Neurology
- Cellular and Molecular Neuroscience
- Physiology (medical)