TY - JOUR
T1 - Primary aldosteronism. Diagnostic evaluation
AU - Young, W. F.
AU - Klee, G. G.
N1 - Funding Information:
From the Departments ofMedicine and Pathology, McMaster University Medical Centre; and The Canadian Red Cross Blood Transfusion Service, Hamilton, Ontario, Canada Some ofthe studies described in this report werefunded by a grant from the Medical Research Council of Canada and a Research· and Development Grant Ifrroomm the Canadian Red Cross Blood Transfusion Service. . Address reprint requests to John G. Kelton, MD, Room 2N34, McMaster University Medical Centre, PO Box 2000, Station A, 1200 Main St West, Hamilton, Ontario ULBNN 3Z5, Canada. © 1989 W.B. Saunders Company. 0887-7963/89/0302-0002$03.00/0
PY - 1988
Y1 - 1988
N2 - For conceptual and practical purposes, the diagnostic approach to primary aldosteronism is divided into two series of studies. First, the diagnosis of primary aldosteronism must be confirmed by demonstrating hypokalemia with inappropriate kaluresis, unsuppressible urine or plasma aldosterone levels, low PRA, and normal glucocorticoid excretion. The second series of studies guides the therapeutic approach by distinguishing APA from IHA. No single test or imaging method has proved to be 100 per cent accurate, and the differentiation between APA and IHA requires a combination of studies.
AB - For conceptual and practical purposes, the diagnostic approach to primary aldosteronism is divided into two series of studies. First, the diagnosis of primary aldosteronism must be confirmed by demonstrating hypokalemia with inappropriate kaluresis, unsuppressible urine or plasma aldosterone levels, low PRA, and normal glucocorticoid excretion. The second series of studies guides the therapeutic approach by distinguishing APA from IHA. No single test or imaging method has proved to be 100 per cent accurate, and the differentiation between APA and IHA requires a combination of studies.
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U2 - 10.1016/s0889-8529(18)30425-0
DO - 10.1016/s0889-8529(18)30425-0
M3 - Review article
C2 - 3042391
AN - SCOPUS:0023902724
SN - 0889-8529
VL - 17
SP - 367
EP - 395
JO - Endocrinology and Metabolism Clinics of North America
JF - Endocrinology and Metabolism Clinics of North America
IS - 2
ER -