TY - JOUR
T1 - Prevention of staphylococcus epidermidis biofilm formation using electrical current
AU - Del Pozo, Jose L.
AU - Rouse, Mark S.
AU - Euba, Gorane
AU - Greenwood-Quaintance, Kerryl E.
AU - Mandrekar, Jayawant N.
AU - Steckelberg, James M.
AU - Patel, Robin
N1 - Publisher Copyright:
© 2014 Società Italiana Biomateriali.
PY - 2014
Y1 - 2014
N2 - A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 103 cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log10 cfu/cm2 were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.
AB - A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 103 cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log10 cfu/cm2 were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.
KW - Biofilm
KW - Electrical current
KW - Electricidal effect
KW - Staphylococcus epidermidis
UR - http://www.scopus.com/inward/record.url?scp=84925135933&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925135933&partnerID=8YFLogxK
U2 - 10.5301/jabfm.5000208
DO - 10.5301/jabfm.5000208
M3 - Article
C2 - 25097026
AN - SCOPUS:84925135933
SN - 2280-8000
VL - 12
SP - 81
EP - 83
JO - Journal of Applied Biomaterials and Functional Materials
JF - Journal of Applied Biomaterials and Functional Materials
IS - 2
ER -