Prevention of staphylococcus epidermidis biofilm formation using electrical current

Jose L. Del Pozo, Mark S. Rouse, Gorane Euba, Kerryl E. Greenwood-Quaintance, Jayawant N. Mandrekar, James M. Steckelberg, Robin Patel

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 103 cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log10 cfu/cm2 were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log10 cfu/cm2 were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.

Original languageEnglish (US)
Pages (from-to)81-83
Number of pages3
JournalJournal of Applied Biomaterials and Fundamental Materials
Volume12
Issue number2
DOIs
StatePublished - Jan 1 2014

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Keywords

  • Biofilm
  • Electrical current
  • Electricidal effect
  • Staphylococcus epidermidis

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomedical Engineering
  • Biomaterials
  • Medicine(all)

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