Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease

Julia Lehman, Dédée F. Murrell, Michael J. Camilleri, Amer N. Kalaaji

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Patients with autoimmune blistering diseases (AIBDs) are particularly susceptible to infection with pathogenic bacteria, fungi, viruses, and mycobacteria. When treated with systemic immunosuppressive medications, these patients may also develop opportunistic infections. Morbidity and mortality associated with infection are considerable in this patient population. Prompt recognition of infection is critical for early and appropriate medical intervention. Preventive measures include avoidance of high-risk environments, diligent attention to skin care and hygiene, administration of immunizations (when contraindications are absent), patient education regarding the symptoms and signs of impending infection, and minimization of iatrogenic immunosuppression where possible. Topical antimicrobial agents can be used for skin colonization or localized infection. The use of systemic antimicrobial agents should be guided by culture and sensitivity results if available. A multidisciplinary approach to care in patients with complex medical issues or acute illness is recommended.

Original languageEnglish (US)
Title of host publicationBlistering Diseases: Clinical Features, Pathogenesis, Treatment
PublisherSpringer Berlin Heidelberg
Pages611-615
Number of pages5
ISBN (Print)9783662456989, 9783662456972
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

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Autoimmune Diseases
Infection
Anti-Infective Agents
Early Medical Intervention
Skin Care
Therapeutics
Opportunistic Infections
Patient Education
Mycobacterium
Immunosuppressive Agents
Hygiene
Immunosuppression
Signs and Symptoms
Immunization
Patient Care
Fungi
Viruses
Morbidity
Bacteria
Skin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lehman, J., Murrell, D. F., Camilleri, M. J., & Kalaaji, A. N. (2015). Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease. In Blistering Diseases: Clinical Features, Pathogenesis, Treatment (pp. 611-615). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-45698-9_65

Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease. / Lehman, Julia; Murrell, Dédée F.; Camilleri, Michael J.; Kalaaji, Amer N.

Blistering Diseases: Clinical Features, Pathogenesis, Treatment. Springer Berlin Heidelberg, 2015. p. 611-615.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lehman, J, Murrell, DF, Camilleri, MJ & Kalaaji, AN 2015, Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease. in Blistering Diseases: Clinical Features, Pathogenesis, Treatment. Springer Berlin Heidelberg, pp. 611-615. https://doi.org/10.1007/978-3-662-45698-9_65
Lehman J, Murrell DF, Camilleri MJ, Kalaaji AN. Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease. In Blistering Diseases: Clinical Features, Pathogenesis, Treatment. Springer Berlin Heidelberg. 2015. p. 611-615 https://doi.org/10.1007/978-3-662-45698-9_65
Lehman, Julia ; Murrell, Dédée F. ; Camilleri, Michael J. ; Kalaaji, Amer N. / Prevention and Treatment of Infections in Patients with Autoimmune Blistering Disease. Blistering Diseases: Clinical Features, Pathogenesis, Treatment. Springer Berlin Heidelberg, 2015. pp. 611-615
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