Abstract
Background Auscultation-based surveys in Ethiopia conducted in the late 1990's reported a rural prevalence of 4.6/1000 and an urban prevalence of 6.4/1000 of rheumatic heart disease (RHD). With echo-based screening, we aimed to estimate the national prevalence of RHD in school children by taking school-based samples from six regions across the country using the 2012 World Heart Federation echocardiographic criteria. Patients and methods We conducted a cross-sectional echocardiographic screening of RHD in school children aged 6–18 years from 28 randomly selected primary and secondary schools found in six different geographic regions of Ethiopia. We used the standardized WHF echocardiographic criteria. Results A total of 3238 children (48.5% females) were screened. The mean age was 13.2 ± 3.2 years. Of these, 44 patients (1.4%) met the WHF criteria for definite RHD, while 15 (0.5%) met the criteria for borderline disease, yielding a prevalence of 19 [13.9–23.4, 95% CI] cases per 1000 school children between the ages of 6–18 years. The majority of those who tested positive were girls (26/44). The prevalence was lowest in children aged 6–9 years and otherwise uniformly distributed across ages 10–18 years. Definite RHD involved the mitral valve in 42 subjects, 39 of whom had mitral regurgitation and 3 with mitral stenosis. The aortic valve was affected in 6 children. The ratio of definite to borderline cases was 2.9. Conclusion This study demonstrated a consistent pattern of high prevalence of asymptomatic RHD with definite disease predominating over borderline involvement across six regions of Ethiopia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 260-263 |
| Number of pages | 4 |
| Journal | International Journal of Cardiology |
| Volume | 221 |
| DOIs | |
| State | Published - Oct 15 2016 |
Fingerprint
Keywords
- Echocardiographic screening
- Rheumatic heart disease in Ethiopia
- World heart federation criteria
ASJC Scopus subject areas
- Medicine(all)
- Cardiology and Cardiovascular Medicine
Cite this
Prevalence of rheumatic heart disease among school children in Ethiopia : A multisite echocardiography-based screening. / Yadeta, Dejuma; Hailu, Abrha; Haileamlak, Abraham; Gedlu, Etsgenet; Guteta, Senbeta; Tefera, Endale; Tigabu, Zemene; Tesfaye, Hagazi; Daniel, Wandimu; Mekonnen, Desalew; Zelalem, Meseret; Tekleab, Yohannes; Alemayehu, Bekele; Mekonnen, Dufera; Azazh, Aklilu; Moges, Tamirat; Hailu, Tedros; Abdosh, Tekabe; Yusuf, Nejib; Ayele, Dawit; Wuobshet, Kindie; Tadele, Henok; Lemma, Kinfe; Shiferaw, Solomon; Giday, Araya; Mekonnen, Demeke; Alemu, Getnet; Zühlke, Liesl; Allison, Thomas G.; Nkomo, Vuyisile T; Engel, Mark E.
In: International Journal of Cardiology, Vol. 221, 15.10.2016, p. 260-263.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of rheumatic heart disease among school children in Ethiopia
T2 - A multisite echocardiography-based screening
AU - Yadeta, Dejuma
AU - Hailu, Abrha
AU - Haileamlak, Abraham
AU - Gedlu, Etsgenet
AU - Guteta, Senbeta
AU - Tefera, Endale
AU - Tigabu, Zemene
AU - Tesfaye, Hagazi
AU - Daniel, Wandimu
AU - Mekonnen, Desalew
AU - Zelalem, Meseret
AU - Tekleab, Yohannes
AU - Alemayehu, Bekele
AU - Mekonnen, Dufera
AU - Azazh, Aklilu
AU - Moges, Tamirat
AU - Hailu, Tedros
AU - Abdosh, Tekabe
AU - Yusuf, Nejib
AU - Ayele, Dawit
AU - Wuobshet, Kindie
AU - Tadele, Henok
AU - Lemma, Kinfe
AU - Shiferaw, Solomon
AU - Giday, Araya
AU - Mekonnen, Demeke
AU - Alemu, Getnet
AU - Zühlke, Liesl
AU - Allison, Thomas G.
AU - Nkomo, Vuyisile T
AU - Engel, Mark E.
PY - 2016/10/15
Y1 - 2016/10/15
N2 - Background Auscultation-based surveys in Ethiopia conducted in the late 1990's reported a rural prevalence of 4.6/1000 and an urban prevalence of 6.4/1000 of rheumatic heart disease (RHD). With echo-based screening, we aimed to estimate the national prevalence of RHD in school children by taking school-based samples from six regions across the country using the 2012 World Heart Federation echocardiographic criteria. Patients and methods We conducted a cross-sectional echocardiographic screening of RHD in school children aged 6–18 years from 28 randomly selected primary and secondary schools found in six different geographic regions of Ethiopia. We used the standardized WHF echocardiographic criteria. Results A total of 3238 children (48.5% females) were screened. The mean age was 13.2 ± 3.2 years. Of these, 44 patients (1.4%) met the WHF criteria for definite RHD, while 15 (0.5%) met the criteria for borderline disease, yielding a prevalence of 19 [13.9–23.4, 95% CI] cases per 1000 school children between the ages of 6–18 years. The majority of those who tested positive were girls (26/44). The prevalence was lowest in children aged 6–9 years and otherwise uniformly distributed across ages 10–18 years. Definite RHD involved the mitral valve in 42 subjects, 39 of whom had mitral regurgitation and 3 with mitral stenosis. The aortic valve was affected in 6 children. The ratio of definite to borderline cases was 2.9. Conclusion This study demonstrated a consistent pattern of high prevalence of asymptomatic RHD with definite disease predominating over borderline involvement across six regions of Ethiopia.
AB - Background Auscultation-based surveys in Ethiopia conducted in the late 1990's reported a rural prevalence of 4.6/1000 and an urban prevalence of 6.4/1000 of rheumatic heart disease (RHD). With echo-based screening, we aimed to estimate the national prevalence of RHD in school children by taking school-based samples from six regions across the country using the 2012 World Heart Federation echocardiographic criteria. Patients and methods We conducted a cross-sectional echocardiographic screening of RHD in school children aged 6–18 years from 28 randomly selected primary and secondary schools found in six different geographic regions of Ethiopia. We used the standardized WHF echocardiographic criteria. Results A total of 3238 children (48.5% females) were screened. The mean age was 13.2 ± 3.2 years. Of these, 44 patients (1.4%) met the WHF criteria for definite RHD, while 15 (0.5%) met the criteria for borderline disease, yielding a prevalence of 19 [13.9–23.4, 95% CI] cases per 1000 school children between the ages of 6–18 years. The majority of those who tested positive were girls (26/44). The prevalence was lowest in children aged 6–9 years and otherwise uniformly distributed across ages 10–18 years. Definite RHD involved the mitral valve in 42 subjects, 39 of whom had mitral regurgitation and 3 with mitral stenosis. The aortic valve was affected in 6 children. The ratio of definite to borderline cases was 2.9. Conclusion This study demonstrated a consistent pattern of high prevalence of asymptomatic RHD with definite disease predominating over borderline involvement across six regions of Ethiopia.
KW - Echocardiographic screening
KW - Rheumatic heart disease in Ethiopia
KW - World heart federation criteria
UR - http://www.scopus.com/inward/record.url?scp=84977648522&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84977648522&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2016.06.232
DO - 10.1016/j.ijcard.2016.06.232
M3 - Article
C2 - 27404686
AN - SCOPUS:84977648522
VL - 221
SP - 260
EP - 263
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -