Prevalence of orthostatic hypotension

Research output: Contribution to journalReview article

182 Scopus citations

Abstract

Orthostatic hypotension (OH) is defined as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic when standing or during head-up tilt testing. The prevalence of OH increases with age, with disorders that affect autonomic nerve transmission, and with increasingly severe orthostatic stress. In normal elderly subjects, the prevalence of OH is reported to be between 5 and 30%. The actual prevalence depends on the conditions during diagnostic testing, such as the frequency of blood pressure recordings, the time of day and the degree of orthostatic stress. Elderly subjects are often taking medications, such as antihypertensives and diuretics that can cause or aggravate OH. Neurological diseases such as diabetic neuropathy, Parkinson's disease, multiple system atrophy and the autonomic neuropathies further increase the likelihood of OH. The development of OH in normal subjects is associated with an increased mortality rate. OH in diabetes is also associated with a significant increase in mortality rate.

Original languageEnglish (US)
Pages (from-to)8-13
Number of pages6
JournalClinical Autonomic Research
Volume18
Issue numberSUPPL. 1
DOIs
StatePublished - Mar 1 2008

Keywords

  • Aging
  • Autonomic nervous system
  • Mortality
  • Neuropathy
  • Orthostatic hypotension
  • Prevalence

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Prevalence of orthostatic hypotension'. Together they form a unique fingerprint.

  • Cite this