Prevalence and Prognostic Significance of Nonsustained Ventricular Tachycardia in Patients With a Left Ventricular Ejection Fraction from 35% to 50%

Sorcha M. Allen, Victor A. Abrich, Paul S. Bibby, Daniel Fishman, Win Kuang Shen, Dan Sorajja

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The risk of life-threatening ventricular arrhythmias in patients with mild-to-moderately reduced left ventricular ejection fraction (LVEF) is unknown. This retrospective case-control study aims to identify the prevalence, risk factors, and outcomes associated with the development of nonsustained ventricular tachycardia (NSVT) as documented on permanent pacemakers or implantable loop recorders in tertiary care center patients with an LVEF of 35% to 50%. Data pertaining to patient demographics, previous medical history, heart failure functional class, echocardiographic parameters, and survival were compared between the groups. Of the 326 patients with an LVEF within the target range, 90 patients (27.6%) had NSVT recorded on their device and 236 patients (72.4%) did not. Compared with patients without NSVT, patients with NSVT had a higher body mass index (28.4 kg/m2 vs 26.8 kg/m2, p = 0.02), more ischemic heart disease (57.8% vs 32.8%, p < 0.0001), higher left atrial volume index (45.8 ml/m2 vs 42.0 ml/m2, p = 0.04), and lower use of antiarrhythmic medications (4.4% vs 11.9%, p = 0.04). The presence of NSVT and the duration of NSVT had no relation to survival, supporting the notion that NSVT is a benign finding in patients with an LVEF of 35% to 50%.

Original languageEnglish (US)
Pages (from-to)330-335
Number of pages6
JournalAmerican Journal of Cardiology
Volume121
Issue number3
DOIs
StatePublished - Feb 1 2018

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Ventricular Tachycardia
Stroke Volume
Survival
Tertiary Care Centers
Myocardial Ischemia
Case-Control Studies
Cardiac Arrhythmias
Body Mass Index
Heart Failure
Demography
Equipment and Supplies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prevalence and Prognostic Significance of Nonsustained Ventricular Tachycardia in Patients With a Left Ventricular Ejection Fraction from 35% to 50%. / Allen, Sorcha M.; Abrich, Victor A.; Bibby, Paul S.; Fishman, Daniel; Shen, Win Kuang; Sorajja, Dan.

In: American Journal of Cardiology, Vol. 121, No. 3, 01.02.2018, p. 330-335.

Research output: Contribution to journalArticle

Allen, Sorcha M. ; Abrich, Victor A. ; Bibby, Paul S. ; Fishman, Daniel ; Shen, Win Kuang ; Sorajja, Dan. / Prevalence and Prognostic Significance of Nonsustained Ventricular Tachycardia in Patients With a Left Ventricular Ejection Fraction from 35% to 50%. In: American Journal of Cardiology. 2018 ; Vol. 121, No. 3. pp. 330-335.
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abstract = "The risk of life-threatening ventricular arrhythmias in patients with mild-to-moderately reduced left ventricular ejection fraction (LVEF) is unknown. This retrospective case-control study aims to identify the prevalence, risk factors, and outcomes associated with the development of nonsustained ventricular tachycardia (NSVT) as documented on permanent pacemakers or implantable loop recorders in tertiary care center patients with an LVEF of 35{\%} to 50{\%}. Data pertaining to patient demographics, previous medical history, heart failure functional class, echocardiographic parameters, and survival were compared between the groups. Of the 326 patients with an LVEF within the target range, 90 patients (27.6{\%}) had NSVT recorded on their device and 236 patients (72.4{\%}) did not. Compared with patients without NSVT, patients with NSVT had a higher body mass index (28.4 kg/m2 vs 26.8 kg/m2, p = 0.02), more ischemic heart disease (57.8{\%} vs 32.8{\%}, p < 0.0001), higher left atrial volume index (45.8 ml/m2 vs 42.0 ml/m2, p = 0.04), and lower use of antiarrhythmic medications (4.4{\%} vs 11.9{\%}, p = 0.04). The presence of NSVT and the duration of NSVT had no relation to survival, supporting the notion that NSVT is a benign finding in patients with an LVEF of 35{\%} to 50{\%}.",
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