Prevalence and correlates of eating disorders in 875 patients with bipolar disorder

Susan L. McElroy, Mark A Frye, Gerhard Hellemann, Lori Altshuler, Gabriele S. Leverich, Trisha Suppes, Paul E. Keck, Willem A. Nolen, Ralph Kupka, Robert M. Post

Research output: Contribution to journalArticle

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Abstract

Objective: Relatively little is known about the co-occurrence of bipolar and eating disorders. We therefore assessed the prevalence and clinical correlates of eating disorders in 875 patients with bipolar disorder. Method: 875 outpatients with DSM-IV bipolar I or II disorder were evaluated with structured diagnostic interviews and clinician- and self-administered questionnaires to determine bipolar and eating disorder diagnoses, other comorbid Axis I disorder diagnoses, and demographic and historical illness characteristics. Results: 125 (14.3%) patients met DSM-IV criteria for at least one comorbid lifetime Axis I eating disorder, with binge eating disorder (N = 77) being more common than bulimia nervosa (n = 42) and anorexia nervosa (N = 27). There were no significant eating disorder comorbidity differences between bipolar I and bipolar II patients. Presence of a lifetime comorbid eating disorder was associated with female gender, younger age, earlier age of onset of mood symptoms and of bipolar disorder, presentation in a mixed episode, greater number of prior mood episodes, history of rapid cycling and suicide attempts, greater mean BMI, obesity and severe obesity, and family history of depression, bipolar disorder, alcoholism, and drug abuse. When the three eating disorder groups were compared, lifetime anorexia nervosa was associated with normal weight and a lifetime anxiety disorder, lifetime bulimia nervosa was associated with overweight, and lifetime binge eating disorder was associated with obesity and severe obesity. Conclusions: Patients with bipolar disorder, especially women, not infrequently have comorbid eating disorders, and this comorbidity is associated with an earlier age of onset and more severe course of bipolar illness.

Original languageEnglish (US)
Pages (from-to)191-198
Number of pages8
JournalJournal of Affective Disorders
Volume128
Issue number3
DOIs
StatePublished - Feb 2011

Fingerprint

Bipolar Disorder
Binge-Eating Disorder
Bulimia Nervosa
Morbid Obesity
Anorexia Nervosa
Age of Onset
Diagnostic and Statistical Manual of Mental Disorders
Comorbidity
Obesity
Feeding and Eating Disorders
Anxiety Disorders
Suicide
Alcoholism
Substance-Related Disorders
Outpatients
Demography
Interviews
Depression
Weights and Measures

Keywords

  • Binge
  • Bipolar disorder
  • Eating disorders

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

McElroy, S. L., Frye, M. A., Hellemann, G., Altshuler, L., Leverich, G. S., Suppes, T., ... Post, R. M. (2011). Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. Journal of Affective Disorders, 128(3), 191-198. https://doi.org/10.1016/j.jad.2010.06.037

Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. / McElroy, Susan L.; Frye, Mark A; Hellemann, Gerhard; Altshuler, Lori; Leverich, Gabriele S.; Suppes, Trisha; Keck, Paul E.; Nolen, Willem A.; Kupka, Ralph; Post, Robert M.

In: Journal of Affective Disorders, Vol. 128, No. 3, 02.2011, p. 191-198.

Research output: Contribution to journalArticle

McElroy, SL, Frye, MA, Hellemann, G, Altshuler, L, Leverich, GS, Suppes, T, Keck, PE, Nolen, WA, Kupka, R & Post, RM 2011, 'Prevalence and correlates of eating disorders in 875 patients with bipolar disorder', Journal of Affective Disorders, vol. 128, no. 3, pp. 191-198. https://doi.org/10.1016/j.jad.2010.06.037
McElroy, Susan L. ; Frye, Mark A ; Hellemann, Gerhard ; Altshuler, Lori ; Leverich, Gabriele S. ; Suppes, Trisha ; Keck, Paul E. ; Nolen, Willem A. ; Kupka, Ralph ; Post, Robert M. / Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. In: Journal of Affective Disorders. 2011 ; Vol. 128, No. 3. pp. 191-198.
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