Prevalence and clinical significance of pancreatic cysts associated with cysts in other organs

Deepak Agrawal, Santo IV Maimone, Richard C.K. Wong, Gerard Isenberg, Ashley Faulx, Amitabh Chak

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and aim: Von Hippel-Lindau disease is associated with serous cysts in the pancreas and kidneys. In this study we determined the prevalence of pancreatic cysts occurring concurrently with other abdominal cysts and tested the hypothesis that these patients might represent a forme fruste of Von Hippel-Lindau disease and be more likely to be serous cysts. Methods: A retrospective chart review of patients undergoing endoscopic ultrasound of pancreatic cysts. Results: A total of 156 patients were included in the study. Eighty-five patients (54.8%) had cyst(s) in the pancreas and at least one other intra-abdominal cyst. These cysts included 24 (27.9%) serous cysts, 30 (34.9%), mucinous cysts, 6 (7%) adenocarcinoma and 25 (29.4%) unknowns. Seventy-one patients (45.2%) had isolated pancreatic cysts. These included 17 (23.9%) serous cysts, 28 (39.5%) mucinous cysts, 4 (5.6%) adenocarcinoma and 22 (31%) unknowns. The odds of serous cysts with concurrent extra-pancreatic and pancreatic cysts compared to odds of serous cysts with pancreatic cysts alone were 1.3 (95% CI: 0.6-2.9). Conclusions: Pancreatic cysts are associated with cysts in other abdominal organs in 54.8% patients. The prevalence of serous cysts was not higher amongst individuals with multiple organ cysts compared to those with only pancreatic cysts.

Original languageEnglish (US)
Pages (from-to)797-801
Number of pages5
JournalDigestive and Liver Disease
Volume43
Issue number10
DOIs
StatePublished - Oct 1 2011
Externally publishedYes

Fingerprint

Pancreatic Cyst
Cysts
von Hippel-Lindau Disease
Pancreas
Adenocarcinoma

Keywords

  • Mucinous cyst
  • Pancreas cyst
  • Serous cyst
  • Von Hippel-Lindau disease

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Prevalence and clinical significance of pancreatic cysts associated with cysts in other organs. / Agrawal, Deepak; Maimone, Santo IV; Wong, Richard C.K.; Isenberg, Gerard; Faulx, Ashley; Chak, Amitabh.

In: Digestive and Liver Disease, Vol. 43, No. 10, 01.10.2011, p. 797-801.

Research output: Contribution to journalArticle

Agrawal, Deepak ; Maimone, Santo IV ; Wong, Richard C.K. ; Isenberg, Gerard ; Faulx, Ashley ; Chak, Amitabh. / Prevalence and clinical significance of pancreatic cysts associated with cysts in other organs. In: Digestive and Liver Disease. 2011 ; Vol. 43, No. 10. pp. 797-801.
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