Prescribing patterns of antidepressant medications for depression in a HMO

David J. Katzelnick, Kenneth A. Kobak, James W. Jefferson, John H. Greist, Heney J. Henk

Research output: Contribution to journalArticle

70 Scopus citations

Abstract

Antidepressant selection and adequacy of treatment were assessed in patients enrolled in a medium-sized, group model HMO from July 1, 1991, to July 1, 1993, who had a diagnosis of depression and who received a prescription for antidepressants during 1992. Overall, 52% of all treatments for depression were of minimum adequate dose and duration. Serotonin reuptake inhibitors had a significantly greater percentage of treatments that were of minimum adequate dose and duration (59%) than did secondary amine tricyclics (47%), tertiary amine tricyclics (44%), bupropion (37%), and trazodone (35%). Psychiatrists had a significantly greater percentage of treatments of minimum adequate dose and duration (57%) than nonpsychiatrists (47%), although the percentage of treatments with SSRIs were approximately the same (53% versus 59%, respectively). Both class of drug and treatment by a psychiatrist were associated with minimum adequate treatment.

Original languageEnglish (US)
Pages (from-to)374-388
Number of pages15
JournalFormulary
Volume31
Issue number5
StatePublished - May 1 1996

ASJC Scopus subject areas

  • Pharmacology (medical)

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    Katzelnick, D. J., Kobak, K. A., Jefferson, J. W., Greist, J. H., & Henk, H. J. (1996). Prescribing patterns of antidepressant medications for depression in a HMO. Formulary, 31(5), 374-388.