Preoperative evaluation of patients with liver disease

A. James Hanje, Tushar C Patel

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Patients with end-stage liver disease often undergo surgery for indications other than liver transplantation. These patients have an increased risk of morbidity and mortality that is related to their underlying liver disease. Assessments of surgical risk provide a basis for discussion of risks and benefits, treatment decision making, and for optimal management of patients for whom surgery is planned. The most useful indicators of surgical risk are indices that predict advanced disease, such as the Child-Turcotte-Pugh score, or those that predict prognosis, such as the Model for End-stage Liver Disease score. Careful preoperative risk assessment, patient selection, and management of various manifestations of advanced disease might decrease morbidity and mortality from nontransplant surgery in patients with liver disease.

Original languageEnglish (US)
Pages (from-to)266-276
Number of pages11
JournalNature Clinical Practice Gastroenterology and Hepatology
Volume4
Issue number5
DOIs
StatePublished - May 2007
Externally publishedYes

Fingerprint

Liver Diseases
End Stage Liver Disease
Morbidity
Mortality
Liver Transplantation
Patient Selection
Decision Making
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Preoperative evaluation of patients with liver disease. / Hanje, A. James; Patel, Tushar C.

In: Nature Clinical Practice Gastroenterology and Hepatology, Vol. 4, No. 5, 05.2007, p. 266-276.

Research output: Contribution to journalArticle

@article{887e06aa1efc4c828b2729cbd83952ea,
title = "Preoperative evaluation of patients with liver disease",
abstract = "Patients with end-stage liver disease often undergo surgery for indications other than liver transplantation. These patients have an increased risk of morbidity and mortality that is related to their underlying liver disease. Assessments of surgical risk provide a basis for discussion of risks and benefits, treatment decision making, and for optimal management of patients for whom surgery is planned. The most useful indicators of surgical risk are indices that predict advanced disease, such as the Child-Turcotte-Pugh score, or those that predict prognosis, such as the Model for End-stage Liver Disease score. Careful preoperative risk assessment, patient selection, and management of various manifestations of advanced disease might decrease morbidity and mortality from nontransplant surgery in patients with liver disease.",
author = "Hanje, {A. James} and Patel, {Tushar C}",
year = "2007",
month = "5",
doi = "10.1038/ncpgasthep0794",
language = "English (US)",
volume = "4",
pages = "266--276",
journal = "Nature Reviews Gastroenterology and Hepatology",
issn = "1759-5045",
publisher = "Nature Publishing Group",
number = "5",

}

TY - JOUR

T1 - Preoperative evaluation of patients with liver disease

AU - Hanje, A. James

AU - Patel, Tushar C

PY - 2007/5

Y1 - 2007/5

N2 - Patients with end-stage liver disease often undergo surgery for indications other than liver transplantation. These patients have an increased risk of morbidity and mortality that is related to their underlying liver disease. Assessments of surgical risk provide a basis for discussion of risks and benefits, treatment decision making, and for optimal management of patients for whom surgery is planned. The most useful indicators of surgical risk are indices that predict advanced disease, such as the Child-Turcotte-Pugh score, or those that predict prognosis, such as the Model for End-stage Liver Disease score. Careful preoperative risk assessment, patient selection, and management of various manifestations of advanced disease might decrease morbidity and mortality from nontransplant surgery in patients with liver disease.

AB - Patients with end-stage liver disease often undergo surgery for indications other than liver transplantation. These patients have an increased risk of morbidity and mortality that is related to their underlying liver disease. Assessments of surgical risk provide a basis for discussion of risks and benefits, treatment decision making, and for optimal management of patients for whom surgery is planned. The most useful indicators of surgical risk are indices that predict advanced disease, such as the Child-Turcotte-Pugh score, or those that predict prognosis, such as the Model for End-stage Liver Disease score. Careful preoperative risk assessment, patient selection, and management of various manifestations of advanced disease might decrease morbidity and mortality from nontransplant surgery in patients with liver disease.

UR - http://www.scopus.com/inward/record.url?scp=34248197097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248197097&partnerID=8YFLogxK

U2 - 10.1038/ncpgasthep0794

DO - 10.1038/ncpgasthep0794

M3 - Article

C2 - 17476209

AN - SCOPUS:34248197097

VL - 4

SP - 266

EP - 276

JO - Nature Reviews Gastroenterology and Hepatology

JF - Nature Reviews Gastroenterology and Hepatology

SN - 1759-5045

IS - 5

ER -