Prenatally diagnosed neck masses: Long-term outcomes and quality of life

Fariha Sheikh, Adesola Akinkuotu, Oluyinka O. Olutoye, Sheena Pimpalwar, Christopher I. Cassady, Caraciolo J. Fernandes, Rodrigo Ruano, Timothy C. Lee, Darrell L. Cass

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17 Scopus citations

Abstract

Purpose To determine long-term outcomes of fetuses with neck masses (NM), including functional and cosmetic results. Methods A retrospective review was performed of all fetuses evaluated for NM from November 2001 to March 2014. Quality of life (QOL) was evaluated using the validated PedsQL™ questionnaire. Results Of 35 fetuses evaluated, 9 died perinatally and 1 died late from tracheostomy complications. NM ranged from 4 to 20 cm (mean, 9.1 cm); 18 were delivered by EXIT. Of 25 surviving patients, 22 had mass resection, 7 requiring more than one procedure. Surviving patients with lymphatic malformations (LM) had the highest incidence of moderate and severe disfigurement and a higher rate of persistent/recurrent disease (100% vs. 31%, p = 0.002) and cranial nerve dysfunction (50% vs. 0%, p = 0.005) compared to those with non-LM diagnoses. Of 9 children attending school, 78% achieve grades of A/B's. QOL for 13 patients revealed a mean score of 83/100 for physical and 78/100 for psychosocial functioning. Median follow-up was 6 years (7 months-17 years). Conclusion Unlike those with teratoma or other lesions, children with congenital cervicofacial LM are at high-risk for persistent disease, nerve dysfunction and moderate-severe disfigurement. There is substantial perinatal morbidity for fetuses with neck masses, but for those surviving, the long-term functional and cognitive outcomes are good.

Original languageEnglish (US)
Pages (from-to)1210-1213
Number of pages4
JournalJournal of Pediatric Surgery
Volume50
Issue number7
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

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Keywords

  • Cervical lymphatic malformation
  • Cervical teratoma
  • Cervical thyroid cyst
  • Cervical vascular malformation
  • Fetal neck mass

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Sheikh, F., Akinkuotu, A., Olutoye, O. O., Pimpalwar, S., Cassady, C. I., Fernandes, C. J., Ruano, R., Lee, T. C., & Cass, D. L. (2015). Prenatally diagnosed neck masses: Long-term outcomes and quality of life. Journal of Pediatric Surgery, 50(7), 1210-1213. https://doi.org/10.1016/j.jpedsurg.2015.02.035