Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access

Scott Nyberg, Christopher B. Hughes, Yunuen M. Valenzuela, Bernice M. Jenson, Margaret M. Benda, James T. McCarthy, Sylvester Sterioff, Mark D Stegall

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The purpose of this study was to determine graft patency and blood flow rates in recipients of a new cuffed ePTFE graft (Venaflo graft) used for hemodialysis access. A pilot study was conducted with 12 (7 men, 5 women) consecutive patients (age range, 36-76 yr; mean, 65 yr). All patients were recipients of a new cuffed PTFE graft placed for hemodialysis access. Seven were high risk because of a prior history of clotted hemodialysis accesses (1-6; mean, 3.3). Blood flow rates were determined by ultrasound dilution technique at 3 month intervals. One year and 2 year overall graft patency rates were 90.9% and 68.2%, respectively. One graft (high risk, six prior grafts) was lost to thrombosis in the first year; two grafts (one high risk, four prior grafts) were lost to thrombosis in the second year of follow-up. No graft thrombosis resulted from stenosis at the graft-vein anastomosis. Blood flow rates ranged from 550 to 2,110 ml/min (mean, 1,086 ml/min; n = 8) when first measured 3 months after graft placement. Similar flow rates were observed at 12 months (mean, 1,043 ml/min; n = 7) and 24 months (mean, 1,014 ml/min; n = 4) in grafts available for comparison. Dialysis flow rates in excess of 350 ml/min were possible with all patent grafts. A cuffed ePTFE graft provided stable blood flow and satisfactory graft patency during 2 years of follow-up, even in high risk patients with a prior history of vascular access thrombosis.

Original languageEnglish (US)
Pages (from-to)333-337
Number of pages5
JournalASAIO Journal
Volume47
Issue number4
StatePublished - 2001

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Grafts
Blood Vessels
Renal Dialysis
Transplants
Flow rate
Thrombosis
Blood
Indicator Dilution Techniques
Dialysis
Polytetrafluoroethylene
Polytetrafluoroethylenes
Dilution
Veins
Pathologic Constriction

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering

Cite this

Nyberg, S., Hughes, C. B., Valenzuela, Y. M., Jenson, B. M., Benda, M. M., McCarthy, J. T., ... Stegall, M. D. (2001). Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access. ASAIO Journal, 47(4), 333-337.

Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access. / Nyberg, Scott; Hughes, Christopher B.; Valenzuela, Yunuen M.; Jenson, Bernice M.; Benda, Margaret M.; McCarthy, James T.; Sterioff, Sylvester; Stegall, Mark D.

In: ASAIO Journal, Vol. 47, No. 4, 2001, p. 333-337.

Research output: Contribution to journalArticle

Nyberg, S, Hughes, CB, Valenzuela, YM, Jenson, BM, Benda, MM, McCarthy, JT, Sterioff, S & Stegall, MD 2001, 'Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access', ASAIO Journal, vol. 47, no. 4, pp. 333-337.
Nyberg S, Hughes CB, Valenzuela YM, Jenson BM, Benda MM, McCarthy JT et al. Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access. ASAIO Journal. 2001;47(4):333-337.
Nyberg, Scott ; Hughes, Christopher B. ; Valenzuela, Yunuen M. ; Jenson, Bernice M. ; Benda, Margaret M. ; McCarthy, James T. ; Sterioff, Sylvester ; Stegall, Mark D. / Preliminary experience with a cuffed ePTFE graft for hemodialysis vascular access. In: ASAIO Journal. 2001 ; Vol. 47, No. 4. pp. 333-337.
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