Pregnancy-related human leukocyte antigen sensitization leading to cardiac allograft vasculopathy and graft failure in a heart transplant recipient: A case report

M. Ginwalla, M. J. Pando, K. K. Khush

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In this report, we present a heart transplant recipient who developed cross-reactive paternal and donor-specific human leukocyte antigen (HLA) class II antibodies during pregnancy, leading to accelerated cardiac allograft vasculopathy and severe allograft dysfunction 17 years after transplantation. This resulted in acute heart failure and ventricular arrhythmias requiring repeat heart transplantation.

Original languageEnglish (US)
Pages (from-to)800-802
Number of pages3
JournalTransplantation Proceedings
Volume45
Issue number2
DOIs
StatePublished - Mar 2013
Externally publishedYes

Fingerprint

HLA Antigens
Allografts
Transplants
Pregnancy
Immunoglobulin Isotypes
Heart Transplantation
Cardiac Arrhythmias
Heart Failure
Transplantation
Tissue Donors
Transplant Recipients

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Pregnancy-related human leukocyte antigen sensitization leading to cardiac allograft vasculopathy and graft failure in a heart transplant recipient : A case report. / Ginwalla, M.; Pando, M. J.; Khush, K. K.

In: Transplantation Proceedings, Vol. 45, No. 2, 03.2013, p. 800-802.

Research output: Contribution to journalArticle

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