Pregnancy and Lupus Nephritis

Andrea G. Kattah, Vesna D. Garovic

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

The management of lupus nephritis in pregnancy presents a diagnostic and therapeutic challenge for providers. Pregnancy creates a series of physiologic changes in the immune system and kidney that may result in an increased risk of disease flare and adverse maternal and fetal outcomes, such as preeclampsia, fetal loss, and preterm delivery. Conception should be delayed until disease is in remission to ensure the best pregnancy outcomes. Maternal disease activity and fetal well-being should be monitored closely by an interdisciplinary team, including obstetricians, rheumatologists, and nephrologists throughout pregnancy. Careful attention must be paid to the dosing and potential teratogenicity of medications.

Original languageEnglish (US)
Pages (from-to)487-499
Number of pages13
JournalSeminars in nephrology
Volume35
Issue number5
DOIs
StatePublished - 2015

Keywords

  • Anti-inflammatory agents/therapeutic use
  • Lupus nephritis
  • Preeclampsia
  • Pregnancy
  • Pregnancy complications
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Nephrology

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