TY - JOUR
T1 - Preeclampsia and the future risk of hypertension
T2 - The pregnant evidence
AU - Garovic, Vesna D.
AU - August, Phyllis
N1 - Funding Information:
Acknowledgments The project described was supported by Award Number K08 HD051714 (V.D. Garovic) from the Eunice Kennedy Shriver National Institute of Child Health & Human Development and by Award Number P-50 AG44170 (V.D. Garovic) from the National Institute on Aging. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Eunice Kennedy Shriver National Institute of Child Health & Human Development or the National Institutes of Health. The writing of the manuscript and the decision to submit it for publication were solely the authors’ responsibilities.
PY - 2013/4
Y1 - 2013/4
N2 - Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 % of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.
AB - Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 % of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.
KW - Cardiovascular disease
KW - Hypercoagulability
KW - Hypertension
KW - Inflammatory response
KW - Metabolic abnormalities
KW - Preeclampsia
KW - Pregnancy
KW - Risk factors
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U2 - 10.1007/s11906-013-0329-4
DO - 10.1007/s11906-013-0329-4
M3 - Review article
C2 - 23397213
AN - SCOPUS:84879605680
SN - 1522-6417
VL - 15
SP - 114
EP - 121
JO - Current Hypertension Reports
JF - Current Hypertension Reports
IS - 2
ER -