Preeclampsia and the future risk of hypertension: The pregnant evidence

Vesna D Garovic, Phyllis August

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 % of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.

Original languageEnglish (US)
Pages (from-to)114-121
Number of pages8
JournalCurrent Hypertension Reports
Volume15
Issue number2
DOIs
StatePublished - Apr 2013

Fingerprint

Pre-Eclampsia
Hypertension
Pregnancy
Maternal Death
Women's Health
Proteinuria
Coronary Disease
Cause of Death
Cardiovascular Diseases
Stroke
Mortality

Keywords

  • Cardiovascular disease
  • Hypercoagulability
  • Hypertension
  • Inflammatory response
  • Metabolic abnormalities
  • Preeclampsia
  • Pregnancy
  • Risk factors

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Preeclampsia and the future risk of hypertension : The pregnant evidence. / Garovic, Vesna D; August, Phyllis.

In: Current Hypertension Reports, Vol. 15, No. 2, 04.2013, p. 114-121.

Research output: Contribution to journalArticle

@article{d4e823eae36243c095787fa61604285e,
title = "Preeclampsia and the future risk of hypertension: The pregnant evidence",
abstract = "Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 {\%} of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.",
keywords = "Cardiovascular disease, Hypercoagulability, Hypertension, Inflammatory response, Metabolic abnormalities, Preeclampsia, Pregnancy, Risk factors",
author = "Garovic, {Vesna D} and Phyllis August",
year = "2013",
month = "4",
doi = "10.1007/s11906-013-0329-4",
language = "English (US)",
volume = "15",
pages = "114--121",
journal = "Current Hypertension Reports",
issn = "1522-6417",
publisher = "Current Medicine Group",
number = "2",

}

TY - JOUR

T1 - Preeclampsia and the future risk of hypertension

T2 - The pregnant evidence

AU - Garovic, Vesna D

AU - August, Phyllis

PY - 2013/4

Y1 - 2013/4

N2 - Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 % of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.

AB - Cardiovascular death rates continue to rise for women under age 55, underlying the importance of focusing on female-specific conditions that may increase cardiovascular risk, including pregnancy-related disorders. Hypertension complicates about 5-10 % of pregnancies. Preeclampsia, a pregnancy-specific condition, is characterized by hypertension and proteinuria after 20 weeks of gestation and remains one of the major causes of maternal deaths in the United States. In addition, preeclampsia may have an impact on women's health beyond their pregnancies, and has been associated with increased risks for future hypertension and cardiovascular disease, such as coronary heart disease and stroke. In this review, we discuss the evidence supporting the association between preeclampsia and future hypertension; possible mechanisms that underlie this association; current approach to women with a history of preeclampsia; and future research that is needed in this field in order to deliver optimal and timely medical care to the affected women.

KW - Cardiovascular disease

KW - Hypercoagulability

KW - Hypertension

KW - Inflammatory response

KW - Metabolic abnormalities

KW - Preeclampsia

KW - Pregnancy

KW - Risk factors

UR - http://www.scopus.com/inward/record.url?scp=84879605680&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879605680&partnerID=8YFLogxK

U2 - 10.1007/s11906-013-0329-4

DO - 10.1007/s11906-013-0329-4

M3 - Article

C2 - 23397213

AN - SCOPUS:84879605680

VL - 15

SP - 114

EP - 121

JO - Current Hypertension Reports

JF - Current Hypertension Reports

SN - 1522-6417

IS - 2

ER -