TY - JOUR
T1 - Predictors of palliative treatment in stage IV colorectal cancer
AU - Osagiede, Osayande
AU - Spaulding, Aaron C.
AU - Frank, Ryan D.
AU - Merchea, Amit
AU - Uitti, Ryan
AU - Ailawadhi, Sikander
AU - Kelley, Scott
AU - Colibaseanu, Dorin
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2019/9
Y1 - 2019/9
N2 - Background: Palliative treatment may be associated with prolonged survival and improved quality of life, but remains underutilized in stage IV colorectal (CRC). We examined a national cohort of stage IV CRC patients to determine the factors associated with palliative treatment. Methods: Stage IV CRC patients, classified based on their survival length (<6 months, 6–24 months, and 24 + months), were analyzed using the American College of Surgeons National Cancer Data Base (2004–2013). Multivariable analysis was performed to evaluate factors associated with palliative treatment. Results: Of 85,981 patients analyzed, 10.9% received palliative treatment. For 6–24 months survival, a more recent year of diagnosis, Medicaid, uninsured status, Mountain and Pacific regions were associated with higher odds of palliative treatment. For those who survived < 6months, older patients had lower odds, while academic centers and residence > 20 miles from treating institutions were associated with increased likelihood of palliative treatment. Conclusions: Palliative treatment in stage IV CRC is associated with a more recent year of diagnosis, Medicaid, academic centers, Mountain and Pacific regions of the US.
AB - Background: Palliative treatment may be associated with prolonged survival and improved quality of life, but remains underutilized in stage IV colorectal (CRC). We examined a national cohort of stage IV CRC patients to determine the factors associated with palliative treatment. Methods: Stage IV CRC patients, classified based on their survival length (<6 months, 6–24 months, and 24 + months), were analyzed using the American College of Surgeons National Cancer Data Base (2004–2013). Multivariable analysis was performed to evaluate factors associated with palliative treatment. Results: Of 85,981 patients analyzed, 10.9% received palliative treatment. For 6–24 months survival, a more recent year of diagnosis, Medicaid, uninsured status, Mountain and Pacific regions were associated with higher odds of palliative treatment. For those who survived < 6months, older patients had lower odds, while academic centers and residence > 20 miles from treating institutions were associated with increased likelihood of palliative treatment. Conclusions: Palliative treatment in stage IV CRC is associated with a more recent year of diagnosis, Medicaid, academic centers, Mountain and Pacific regions of the US.
KW - Colorectal neoplasms
KW - National cancer database
KW - Palliative treatment
KW - Retrospective cohort study
UR - http://www.scopus.com/inward/record.url?scp=85058514111&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85058514111&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2018.12.016
DO - 10.1016/j.amjsurg.2018.12.016
M3 - Article
C2 - 30578033
AN - SCOPUS:85058514111
SN - 0002-9610
VL - 218
SP - 514
EP - 520
JO - American journal of surgery
JF - American journal of surgery
IS - 3
ER -