Predictors of palliative treatment in stage IV colorectal cancer

Osayande Osagiede, Aaron Spaulding, Ryan D. Frank, Amit Merchea, Ryan Uitti, Sikander Ailawadhi, Scott Kelley, Dorin Colibaseanu

Research output: Contribution to journalArticle

Abstract

Background: Palliative treatment may be associated with prolonged survival and improved quality of life, but remains underutilized in stage IV colorectal (CRC). We examined a national cohort of stage IV CRC patients to determine the factors associated with palliative treatment. Methods: Stage IV CRC patients, classified based on their survival length (<6 months, 6–24 months, and 24 + months), were analyzed using the American College of Surgeons National Cancer Data Base (2004–2013). Multivariable analysis was performed to evaluate factors associated with palliative treatment. Results: Of 85,981 patients analyzed, 10.9% received palliative treatment. For 6–24 months survival, a more recent year of diagnosis, Medicaid, uninsured status, Mountain and Pacific regions were associated with higher odds of palliative treatment. For those who survived < 6months, older patients had lower odds, while academic centers and residence > 20 miles from treating institutions were associated with increased likelihood of palliative treatment. Conclusions: Palliative treatment in stage IV CRC is associated with a more recent year of diagnosis, Medicaid, academic centers, Mountain and Pacific regions of the US.

Original languageEnglish (US)
JournalAmerican Journal of Surgery
DOIs
StateAccepted/In press - Jan 1 2018

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Palliative Care
Colorectal Neoplasms
Survival
Medicaid
Quality of Life

Keywords

  • Colorectal neoplasms
  • National cancer database
  • Palliative treatment
  • Retrospective cohort study

ASJC Scopus subject areas

  • Surgery

Cite this

Predictors of palliative treatment in stage IV colorectal cancer. / Osagiede, Osayande; Spaulding, Aaron; Frank, Ryan D.; Merchea, Amit; Uitti, Ryan; Ailawadhi, Sikander; Kelley, Scott; Colibaseanu, Dorin.

In: American Journal of Surgery, 01.01.2018.

Research output: Contribution to journalArticle

Osagiede, Osayande ; Spaulding, Aaron ; Frank, Ryan D. ; Merchea, Amit ; Uitti, Ryan ; Ailawadhi, Sikander ; Kelley, Scott ; Colibaseanu, Dorin. / Predictors of palliative treatment in stage IV colorectal cancer. In: American Journal of Surgery. 2018.
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AU - Frank, Ryan D.

AU - Merchea, Amit

AU - Uitti, Ryan

AU - Ailawadhi, Sikander

AU - Kelley, Scott

AU - Colibaseanu, Dorin

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