Predictors of elevated cardiac enzyme levels in hospitalized patients with atrial fibrillation and no known coronary artery disease

Karyne L. Vinales, Mohammad Q. Najib, Punnaiah C. Marella, Minako Katayama, Hari P Chaliki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We retrospectively studied the predictive capabilities of elevated cardiac enzyme levels in terms of the prognosis of patients who were hospitalized with atrial fibrillation and who had no known coronary artery disease. Among 321 patients with atrial fibrillation, 60 without known coronary artery disease had their cardiac enzyme concentrations measured during hospitalization and underwent stress testing or cardiac catheterization within 12 months before or after hospitalization. We then compared the clinical and electrocardiographic characteristics of the 20 patients who had elevated cardiac enzyme levels and the 40 patients who had normal levels. Age, sex, and comorbidities did not differ between the groups. In the patients with elevated cardiac enzyme levels, the mean concentrations of troponin T and creatine kinase-MB isoenzymes were 0.08 ± 0.08 ng/mL and 6.49 ± 4.94 ng/mL, respectively. In univariate analyses, only peak heart rate during atrial tachyarrhythmia was predictive of elevated enzyme levels (P

Original languageEnglish (US)
Pages (from-to)38-42
Number of pages5
JournalTexas Heart Institute Journal
Volume43
Issue number1
DOIs
StatePublished - Feb 1 2016

Fingerprint

Atrial Fibrillation
Coronary Artery Disease
Enzymes
Hospitalization
MB Form Creatine Kinase
Troponin T
Cardiac Catheterization
Tachycardia
Isoenzymes
Comorbidity
Heart Rate

Keywords

  • Atrial fibrillation/blood/physiopathology
  • Biological markers/blood
  • Creatine kinase/blood
  • Heart diseases/diagnosis
  • Hospitalization
  • Predictive value of tests
  • Prognosis
  • Retrospective studies
  • Risk assessment/methods
  • Troponin/blood

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Predictors of elevated cardiac enzyme levels in hospitalized patients with atrial fibrillation and no known coronary artery disease. / Vinales, Karyne L.; Najib, Mohammad Q.; Marella, Punnaiah C.; Katayama, Minako; Chaliki, Hari P.

In: Texas Heart Institute Journal, Vol. 43, No. 1, 01.02.2016, p. 38-42.

Research output: Contribution to journalArticle

Vinales, Karyne L. ; Najib, Mohammad Q. ; Marella, Punnaiah C. ; Katayama, Minako ; Chaliki, Hari P. / Predictors of elevated cardiac enzyme levels in hospitalized patients with atrial fibrillation and no known coronary artery disease. In: Texas Heart Institute Journal. 2016 ; Vol. 43, No. 1. pp. 38-42.
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