Predictors of complete endoscopic mucosal resection of flat and depressed gastrointestinal neoplasia of the colon

Timothy A. Woodward, Michael G. Heckman, Patrick Cleveland, Silvio De Melo, Massimo Raimondo, Michael Wallace

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

OBJECTIVES: We evaluated risk factors for residual neoplasia on first follow-up endoscopy after colonic endoscopic mucosal resections (EMRs). METHODS: This retrospective study in a high-volume EMR tertiary-referral center examined EMRs on 423 colonic lesions in 313 patients. RESULTS: Residual neoplasia at first follow-up endoscopy was present following 12% of colonic EMRs. Single-variable analysis showed evidence of an increased risk of residual neoplasia for larger polyps, polyps without a lifting sign, and polyps removed piecemeal. In multivariable analysis, only use of the piecemeal method was independently associated with residual neoplasia. CONCLUSIONS: Additional procedures are needed to complete resection in more than 1 in 10 colonic EMRs. Residual neoplasia occurs more often with piecemeal resection. Close surveillance after EMR and the use of newer methods to further reduce residual neoplasia are needed.

Original languageEnglish (US)
Pages (from-to)650-654
Number of pages5
JournalAmerican Journal of Gastroenterology
Volume107
Issue number5
DOIs
StatePublished - May 2012

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Colon
Polyps
Neoplasms
Endoscopy
Tertiary Care Centers
Endoscopic Mucosal Resection
Retrospective Studies

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Predictors of complete endoscopic mucosal resection of flat and depressed gastrointestinal neoplasia of the colon. / Woodward, Timothy A.; Heckman, Michael G.; Cleveland, Patrick; De Melo, Silvio; Raimondo, Massimo; Wallace, Michael.

In: American Journal of Gastroenterology, Vol. 107, No. 5, 05.2012, p. 650-654.

Research output: Contribution to journalArticle

Woodward, Timothy A. ; Heckman, Michael G. ; Cleveland, Patrick ; De Melo, Silvio ; Raimondo, Massimo ; Wallace, Michael. / Predictors of complete endoscopic mucosal resection of flat and depressed gastrointestinal neoplasia of the colon. In: American Journal of Gastroenterology. 2012 ; Vol. 107, No. 5. pp. 650-654.
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