Prediction of amikacin dose requirements in neutropenic patients with haematological disease

C. S. Zent, R. Allin, P. I. Folb

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Abstract

This study reports on the use of an easily applied Bayesian forecasting programme (OPT; Clydesolf) to predict amikacin dose requirements in 10 patients with haematological disease and neutropenic fever. OPT-determined dose adjustment achieved therapeutic drug levels for 80% of the peak and 94% of the trough measurements.

Original languageEnglish (US)
Pages (from-to)853-854
Number of pages2
JournalSouth African Medical Journal
Volume83
Issue number11
StatePublished - Dec 1 1993

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ASJC Scopus subject areas

  • Medicine(all)

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