Prediction of amikacin dose requirements in neutropenic patients with haematological disease

C. S. Zent, R. Allin, P. I. Folb

Research output: Contribution to journalArticle

Abstract

This study reports on the use of an easily applied Bayesian forecasting programme (OPT; Clydesolf) to predict amikacin dose requirements in 10 patients with haematological disease and neutropenic fever. OPT-determined dose adjustment achieved therapeutic drug levels for 80% of the peak and 94% of the trough measurements.

Original languageEnglish (US)
Pages (from-to)853-854
Number of pages2
JournalSouth African Medical Journal
Volume83
Issue number11
StatePublished - 1993
Externally publishedYes

Fingerprint

Amikacin
Hematologic Diseases
Fever
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prediction of amikacin dose requirements in neutropenic patients with haematological disease. / Zent, C. S.; Allin, R.; Folb, P. I.

In: South African Medical Journal, Vol. 83, No. 11, 1993, p. 853-854.

Research output: Contribution to journalArticle

Zent, C. S. ; Allin, R. ; Folb, P. I. / Prediction of amikacin dose requirements in neutropenic patients with haematological disease. In: South African Medical Journal. 1993 ; Vol. 83, No. 11. pp. 853-854.
@article{cf25612ca40449269f651cae485530b1,
title = "Prediction of amikacin dose requirements in neutropenic patients with haematological disease",
abstract = "This study reports on the use of an easily applied Bayesian forecasting programme (OPT; Clydesolf) to predict amikacin dose requirements in 10 patients with haematological disease and neutropenic fever. OPT-determined dose adjustment achieved therapeutic drug levels for 80{\%} of the peak and 94{\%} of the trough measurements.",
author = "Zent, {C. S.} and R. Allin and Folb, {P. I.}",
year = "1993",
language = "English (US)",
volume = "83",
pages = "853--854",
journal = "South African Medical Journal",
issn = "0256-9574",
publisher = "South African Medical Association",
number = "11",

}

TY - JOUR

T1 - Prediction of amikacin dose requirements in neutropenic patients with haematological disease

AU - Zent, C. S.

AU - Allin, R.

AU - Folb, P. I.

PY - 1993

Y1 - 1993

N2 - This study reports on the use of an easily applied Bayesian forecasting programme (OPT; Clydesolf) to predict amikacin dose requirements in 10 patients with haematological disease and neutropenic fever. OPT-determined dose adjustment achieved therapeutic drug levels for 80% of the peak and 94% of the trough measurements.

AB - This study reports on the use of an easily applied Bayesian forecasting programme (OPT; Clydesolf) to predict amikacin dose requirements in 10 patients with haematological disease and neutropenic fever. OPT-determined dose adjustment achieved therapeutic drug levels for 80% of the peak and 94% of the trough measurements.

UR - http://www.scopus.com/inward/record.url?scp=0027746177&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027746177&partnerID=8YFLogxK

M3 - Article

VL - 83

SP - 853

EP - 854

JO - South African Medical Journal

JF - South African Medical Journal

SN - 0256-9574

IS - 11

ER -