Prediction and prevention of musculoskeletal injury: A paradigm shift in methodology

C. E. Quatman, C. C. Quatman, Timothy Hewett

Research output: Contribution to journalReview article

31 Citations (Scopus)

Abstract

Traditional methods employed to study musculoskeletal injury mechanisms and joint biomechanics utilise in vivo or in vitro techniques. The advent of new technology and improved methods has also given rise to in silico (computer modelling) techniques. Under the current research paradigm, in vivo, in vitro and in silico methods independently provide information regarding the mechanisms and prevention of musculoskeletal injury. However, individually, each of these methods has multiple, inherent limitations and is likely to provide incomplete answers about multifactorial, complex injury conditions. The purpose of this treatise is to review current methods used to study, understand, and prevent musculoskeletal injury and to develop new conceptualmethodological frameworks that may help create a paradigm shift in musculoskeletal injury prevention research. We term the fusion of these three techniques in simulacra amalgama, or simply in sim, meaning a ''union of models done on the likeness of phenomena.'' Anterior cruciate ligament (ACL) injury will be employed as a model example for the utility and applicability of the proposed, synthesised approach. Shifting the current experimental paradigm to incorporate a multifaceted, multidisciplinary, integration of in vivo, in vitro and in silico methods into the proposed in sim approaches may provide a platform for a more comprehensive understanding of the relationships between complex joint biomechanics and observed injury mechanisms.

Original languageEnglish (US)
Pages (from-to)1100-1107
Number of pages8
JournalBritish Journal of Sports Medicine
Volume43
Issue number14
DOIs
StatePublished - Dec 2009
Externally publishedYes

Fingerprint

Wounds and Injuries
Computer Simulation
Biomechanical Phenomena
Joints
Research
Technology
In Vitro Techniques

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Prediction and prevention of musculoskeletal injury : A paradigm shift in methodology. / Quatman, C. E.; Quatman, C. C.; Hewett, Timothy.

In: British Journal of Sports Medicine, Vol. 43, No. 14, 12.2009, p. 1100-1107.

Research output: Contribution to journalReview article

@article{6c7b6d330332445ab7e5e5b019dffa34,
title = "Prediction and prevention of musculoskeletal injury: A paradigm shift in methodology",
abstract = "Traditional methods employed to study musculoskeletal injury mechanisms and joint biomechanics utilise in vivo or in vitro techniques. The advent of new technology and improved methods has also given rise to in silico (computer modelling) techniques. Under the current research paradigm, in vivo, in vitro and in silico methods independently provide information regarding the mechanisms and prevention of musculoskeletal injury. However, individually, each of these methods has multiple, inherent limitations and is likely to provide incomplete answers about multifactorial, complex injury conditions. The purpose of this treatise is to review current methods used to study, understand, and prevent musculoskeletal injury and to develop new conceptualmethodological frameworks that may help create a paradigm shift in musculoskeletal injury prevention research. We term the fusion of these three techniques in simulacra amalgama, or simply in sim, meaning a ''union of models done on the likeness of phenomena.'' Anterior cruciate ligament (ACL) injury will be employed as a model example for the utility and applicability of the proposed, synthesised approach. Shifting the current experimental paradigm to incorporate a multifaceted, multidisciplinary, integration of in vivo, in vitro and in silico methods into the proposed in sim approaches may provide a platform for a more comprehensive understanding of the relationships between complex joint biomechanics and observed injury mechanisms.",
author = "Quatman, {C. E.} and Quatman, {C. C.} and Timothy Hewett",
year = "2009",
month = "12",
doi = "10.1136/bjsm.2009.065482",
language = "English (US)",
volume = "43",
pages = "1100--1107",
journal = "British Journal of Sports Medicine",
issn = "0306-3674",
publisher = "BMJ Publishing Group",
number = "14",

}

TY - JOUR

T1 - Prediction and prevention of musculoskeletal injury

T2 - A paradigm shift in methodology

AU - Quatman, C. E.

AU - Quatman, C. C.

AU - Hewett, Timothy

PY - 2009/12

Y1 - 2009/12

N2 - Traditional methods employed to study musculoskeletal injury mechanisms and joint biomechanics utilise in vivo or in vitro techniques. The advent of new technology and improved methods has also given rise to in silico (computer modelling) techniques. Under the current research paradigm, in vivo, in vitro and in silico methods independently provide information regarding the mechanisms and prevention of musculoskeletal injury. However, individually, each of these methods has multiple, inherent limitations and is likely to provide incomplete answers about multifactorial, complex injury conditions. The purpose of this treatise is to review current methods used to study, understand, and prevent musculoskeletal injury and to develop new conceptualmethodological frameworks that may help create a paradigm shift in musculoskeletal injury prevention research. We term the fusion of these three techniques in simulacra amalgama, or simply in sim, meaning a ''union of models done on the likeness of phenomena.'' Anterior cruciate ligament (ACL) injury will be employed as a model example for the utility and applicability of the proposed, synthesised approach. Shifting the current experimental paradigm to incorporate a multifaceted, multidisciplinary, integration of in vivo, in vitro and in silico methods into the proposed in sim approaches may provide a platform for a more comprehensive understanding of the relationships between complex joint biomechanics and observed injury mechanisms.

AB - Traditional methods employed to study musculoskeletal injury mechanisms and joint biomechanics utilise in vivo or in vitro techniques. The advent of new technology and improved methods has also given rise to in silico (computer modelling) techniques. Under the current research paradigm, in vivo, in vitro and in silico methods independently provide information regarding the mechanisms and prevention of musculoskeletal injury. However, individually, each of these methods has multiple, inherent limitations and is likely to provide incomplete answers about multifactorial, complex injury conditions. The purpose of this treatise is to review current methods used to study, understand, and prevent musculoskeletal injury and to develop new conceptualmethodological frameworks that may help create a paradigm shift in musculoskeletal injury prevention research. We term the fusion of these three techniques in simulacra amalgama, or simply in sim, meaning a ''union of models done on the likeness of phenomena.'' Anterior cruciate ligament (ACL) injury will be employed as a model example for the utility and applicability of the proposed, synthesised approach. Shifting the current experimental paradigm to incorporate a multifaceted, multidisciplinary, integration of in vivo, in vitro and in silico methods into the proposed in sim approaches may provide a platform for a more comprehensive understanding of the relationships between complex joint biomechanics and observed injury mechanisms.

UR - http://www.scopus.com/inward/record.url?scp=71649099621&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=71649099621&partnerID=8YFLogxK

U2 - 10.1136/bjsm.2009.065482

DO - 10.1136/bjsm.2009.065482

M3 - Review article

C2 - 19884108

AN - SCOPUS:71649099621

VL - 43

SP - 1100

EP - 1107

JO - British Journal of Sports Medicine

JF - British Journal of Sports Medicine

SN - 0306-3674

IS - 14

ER -