Pre-eclamptic pregnancies: An opportunity to identify women at risk for future cardiovascular disease

Iasmina M. Craici, Steven J. Wagner, Suzanne R. Hayman, Vesna D. Garovic

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a two fold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.

Original languageEnglish (US)
Pages (from-to)133-135
Number of pages3
JournalWomen's Health
Volume4
Issue number2
DOIs
StatePublished - Mar 2008

Keywords

  • Breast cancer
  • Cancer
  • Cardiovascular disease
  • Deep venous thrombosis
  • Eclampsia
  • Ischemic hearth disease
  • Meta-analysis
  • Mortality
  • Pre-eclampsia
  • Stroke

ASJC Scopus subject areas

  • General Medicine

Fingerprint

Dive into the research topics of 'Pre-eclamptic pregnancies: An opportunity to identify women at risk for future cardiovascular disease'. Together they form a unique fingerprint.

Cite this