Pre-eclamptic pregnancies: An opportunity to identify women at risk for future cardiovascular disease

Iasmina M. Craici, Steven J. Wagner, Suzanne R. Hayman, Vesna D Garovic

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a two fold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.

Original languageEnglish (US)
Pages (from-to)133-135
Number of pages3
JournalWomen's Health
Volume4
Issue number2
DOIs
StatePublished - Mar 2008

Fingerprint

Pre-Eclampsia
Cardiovascular Diseases
Pregnancy
Eclampsia
Mortality
Venous Thrombosis
Myocardial Ischemia
Meta-Analysis
History
Stroke
Hypertension
Neoplasms
Therapeutics

Keywords

  • Breast cancer
  • Cancer
  • Cardiovascular disease
  • Deep venous thrombosis
  • Eclampsia
  • Ischemic hearth disease
  • Meta-analysis
  • Mortality
  • Pre-eclampsia
  • Stroke

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pre-eclamptic pregnancies : An opportunity to identify women at risk for future cardiovascular disease. / Craici, Iasmina M.; Wagner, Steven J.; Hayman, Suzanne R.; Garovic, Vesna D.

In: Women's Health, Vol. 4, No. 2, 03.2008, p. 133-135.

Research output: Contribution to journalArticle

Craici, Iasmina M. ; Wagner, Steven J. ; Hayman, Suzanne R. ; Garovic, Vesna D. / Pre-eclamptic pregnancies : An opportunity to identify women at risk for future cardiovascular disease. In: Women's Health. 2008 ; Vol. 4, No. 2. pp. 133-135.
@article{7af1d7fe3a1649cd9c9f2c54c800fe97,
title = "Pre-eclamptic pregnancies: An opportunity to identify women at risk for future cardiovascular disease",
abstract = "Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a two fold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.",
keywords = "Breast cancer, Cancer, Cardiovascular disease, Deep venous thrombosis, Eclampsia, Ischemic hearth disease, Meta-analysis, Mortality, Pre-eclampsia, Stroke",
author = "Craici, {Iasmina M.} and Wagner, {Steven J.} and Hayman, {Suzanne R.} and Garovic, {Vesna D}",
year = "2008",
month = "3",
doi = "10.2217/17455057.4.2.133",
language = "English (US)",
volume = "4",
pages = "133--135",
journal = "Women's health (London, England)",
issn = "1745-5065",
publisher = "Future Medicine Ltd.",
number = "2",

}

TY - JOUR

T1 - Pre-eclamptic pregnancies

T2 - An opportunity to identify women at risk for future cardiovascular disease

AU - Craici, Iasmina M.

AU - Wagner, Steven J.

AU - Hayman, Suzanne R.

AU - Garovic, Vesna D

PY - 2008/3

Y1 - 2008/3

N2 - Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a two fold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.

AB - Evidence has emerged over the years suggesting that women who develop hypertensive pregnancy disorders, most notably pre-eclampsia, are at an increased risk for cardiovascular disease later in life. In this study, a systematic review and meta-analysis were performed, assessing the future risks of cardiovascular disease, cancer and all-cause mortality in women with a history of pre-eclampsia and eclampsia. Women with a history of pre-eclampsia or eclampsia compared with women without such a history, had an increased risk for cardiovascular disease, including a fourfold increased risk for hypertension, a two fold increased risk for ischemic heart disease, stroke and deep venous thrombosis, and a 1.5-times higher all-cause mortality. The study suggests that affected women may be eligible for preventive therapies at an earlier age, especially if future studies establish the role of pre-eclampsia as an independent cardiovascular risk factor.

KW - Breast cancer

KW - Cancer

KW - Cardiovascular disease

KW - Deep venous thrombosis

KW - Eclampsia

KW - Ischemic hearth disease

KW - Meta-analysis

KW - Mortality

KW - Pre-eclampsia

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=41949124176&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41949124176&partnerID=8YFLogxK

U2 - 10.2217/17455057.4.2.133

DO - 10.2217/17455057.4.2.133

M3 - Article

C2 - 19072514

AN - SCOPUS:41949124176

VL - 4

SP - 133

EP - 135

JO - Women's health (London, England)

JF - Women's health (London, England)

SN - 1745-5065

IS - 2

ER -