Pragmatic cluster randomized trial to evaluate effectiveness and implementation of EHR-facilitated collaborative symptom control in cancer (E2C2): addendum

Jeph Herrin; Lila J. Finney Rutten; Kathryn J. Ruddy; Kurt Kroenke; Andrea L. Cheville

doi:10.1186/s13063-022-06983-6

Pragmatic cluster randomized trial to evaluate effectiveness and implementation of EHR-facilitated collaborative symptom control in cancer (E2C2): addendum

Jeph Herrin, Lila J. Finney Rutten, Kathryn J. Ruddy, Kurt Kroenke, Andrea L. Cheville

Research output: Contribution to journal › Article › peer-review

Abstract

We previously described the hypotheses, outcomes, design, and analysis for E2C2, a pragmatic stepped-wedge trial to assess an intervention to improve symptom control in patients with cancer. Subsequent consideration of the design and cohort led to the addition of a second primary hypothesis. This article describes and presents the rationale for this second hypothesis. This addendum also details a revised analytic approach, necessitated by inconsistencies in the original analytic plan. The design, outcomes, and other aspects of the protocol remain unchanged.

Original language	English (US)
Pages (from-to)	21
Number of pages	1
Journal	Trials
Volume	24
Issue number	1
DOIs	https://doi.org/10.1186/s13063-022-06983-6
State	Published - Jan 9 2023

Keywords

Electronic health record
Neoplasm
Pain
Palliative care
Patient care team
Patient-reported outcome measure
Quality of life
Self-management
Survivor
Systems integration

ASJC Scopus subject areas

Medicine (miscellaneous)
Pharmacology (medical)

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10.1186/s13063-022-06983-6

Cite this

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abstract = "We previously described the hypotheses, outcomes, design, and analysis for E2C2, a pragmatic stepped-wedge trial to assess an intervention to improve symptom control in patients with cancer. Subsequent consideration of the design and cohort led to the addition of a second primary hypothesis. This article describes and presents the rationale for this second hypothesis. This addendum also details a revised analytic approach, necessitated by inconsistencies in the original analytic plan. The design, outcomes, and other aspects of the protocol remain unchanged.",

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AU - Ruddy, Kathryn J.

AU - Kroenke, Kurt

AU - Cheville, Andrea L.

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KW - Patient care team

KW - Patient-reported outcome measure

KW - Quality of life

KW - Self-management

KW - Survivor

KW - Systems integration

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Pragmatic cluster randomized trial to evaluate effectiveness and implementation of EHR-facilitated collaborative symptom control in cancer (E2C2): addendum

Abstract

Keywords

ASJC Scopus subject areas

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