TY - JOUR
T1 - Practice parameters for the medical therapy of obstructive sleep apnea
T2 - Standards of Practice Committee of the American Academy of Sleep Medicine
AU - Morgenthaler, Timothy I.
AU - Kapen, Sheldon
AU - Lee-Chiong, Teofilo
AU - Alessi, Cathy
AU - Boehlecke, Brian
AU - Brown, Terry
AU - Coleman, Jack
AU - Friedman, Leah
AU - Kapur, Vishesh
AU - Owens, Judith
AU - Pancer, Jeffrey
AU - Swick, Todd
PY - 2006/8/1
Y1 - 2006/8/1
N2 - Therapies for obstructive sleep apnea other than positive airway pressure, oral appliances, and surgical modifications of the upper airway are reviewed in this practice parameter. Several of these therapies such as weight loss and positional therapy hold some promise. Others, such as serotonergic agents, may gain credibility in the future but lack well-designed clinical trials. No practice parameters could be developed for a number of possible therapeutic modalities that had little or no evidence-based data on which to form a conclusion. The role of an organized, targeted weight-loss program either as a single therapy or as a supplement to PAP needs to be clarified. Although bariatric surgery is increasingly performed for refractory medically complicated obesity, its long-term effectiveness in treatment of obstructive sleep apnea in morbidly obese patients is not yet demonstrated. Positional therapy, or methods for preventing sleep in the supine position, has probably been underutilized due to lack of easily measured predictive factors and randomized controlled trials.
AB - Therapies for obstructive sleep apnea other than positive airway pressure, oral appliances, and surgical modifications of the upper airway are reviewed in this practice parameter. Several of these therapies such as weight loss and positional therapy hold some promise. Others, such as serotonergic agents, may gain credibility in the future but lack well-designed clinical trials. No practice parameters could be developed for a number of possible therapeutic modalities that had little or no evidence-based data on which to form a conclusion. The role of an organized, targeted weight-loss program either as a single therapy or as a supplement to PAP needs to be clarified. Although bariatric surgery is increasingly performed for refractory medically complicated obesity, its long-term effectiveness in treatment of obstructive sleep apnea in morbidly obese patients is not yet demonstrated. Positional therapy, or methods for preventing sleep in the supine position, has probably been underutilized due to lack of easily measured predictive factors and randomized controlled trials.
KW - Bariatric surgery
KW - Medical therapy
KW - Obstructive sleep apnea
KW - Positional therapy
KW - Selective serotonergic uptake inhibitors
KW - Supplementary oxygen
KW - Weight reduction
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U2 - 10.1093/sleep/29.8.1031
DO - 10.1093/sleep/29.8.1031
M3 - Review article
C2 - 16944671
AN - SCOPUS:33747462560
SN - 0161-8105
VL - 29
SP - 1031
EP - 1035
JO - Sleep
JF - Sleep
IS - 8
ER -