Postprandial duodenal function in man

Laurence J Miller, J. R. Malagelada, V. L W Go

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Duodenal function was studied in 11 healthy volunteers after intragastric instillation of a mixed semi-elemental meal. The duodenum accepted chyme of varying pH, osmolality, and nutrient concentration; and, as a result of biliary, pancreatic, and enteric secretion as well as absorption, it delivered chyme with nearly constant pH, osmolality, and nutrient concentration to the jejunum. The flow rate and nutrient load of jejunal chyme varied. The duodenum absorbed more carbohydrate than lipid and less protein, taking up each nutrient at a constant rate during most of the postprandial period. The percentage of nutrient load absorbed was greatest in the late postprandial period, when flow rate, nutrient load, and concentrations were low.

Original languageEnglish (US)
Pages (from-to)699-706
Number of pages8
JournalGut
Volume19
Issue number8
StatePublished - 1978

Fingerprint

Food
Postprandial Period
Duodenum
Osmolar Concentration
Jejunum
Meals
Healthy Volunteers
Carbohydrates
Lipids
Proteins

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Miller, L. J., Malagelada, J. R., & Go, V. L. W. (1978). Postprandial duodenal function in man. Gut, 19(8), 699-706.

Postprandial duodenal function in man. / Miller, Laurence J; Malagelada, J. R.; Go, V. L W.

In: Gut, Vol. 19, No. 8, 1978, p. 699-706.

Research output: Contribution to journalArticle

Miller, LJ, Malagelada, JR & Go, VLW 1978, 'Postprandial duodenal function in man', Gut, vol. 19, no. 8, pp. 699-706.
Miller LJ, Malagelada JR, Go VLW. Postprandial duodenal function in man. Gut. 1978;19(8):699-706.
Miller, Laurence J ; Malagelada, J. R. ; Go, V. L W. / Postprandial duodenal function in man. In: Gut. 1978 ; Vol. 19, No. 8. pp. 699-706.
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