Postoperative Seroma Formation After Posterior Cervical Fusion with Use of RhBMP-2: A Report of Two Cases

Nathan R. Wanderman, Nicholas J. Drayer, Marko Tomov, Jeremy W. Reifsnyder, Bayard Carlson, William Robinson, Daniel G. Kang, Brett Freedman

Research output: Contribution to journalArticle

Abstract

CASE: We present 2 cases of postoperative seroma formation following posterior cervical fusion with the use of recombinant human bone morphogenetic protein-2 (rhBMP-2). CONCLUSION: Although some who advocate for the off-label use of rhBMP-2 in patients undergoing posterior cervical spine fusion believe it to be safe, relatively little has been published regarding complication rates. We believe that rhBMP-2 carries a risk of seroma formation in patients who undergo posterior cervical fusion, which necessitates the use of a postoperative drain. Surgeons should have a low threshold for obtaining postoperative magnetic resonance imaging in a symptomatic patient.

Original languageEnglish (US)
Pages (from-to)e74
JournalJBJS case connector
Volume8
Issue number3
DOIs
StatePublished - Jul 1 2018

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Seroma
Off-Label Use
Spine
Magnetic Resonance Imaging
recombinant human bone morphogenetic protein-2

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Postoperative Seroma Formation After Posterior Cervical Fusion with Use of RhBMP-2 : A Report of Two Cases. / Wanderman, Nathan R.; Drayer, Nicholas J.; Tomov, Marko; Reifsnyder, Jeremy W.; Carlson, Bayard; Robinson, William; Kang, Daniel G.; Freedman, Brett.

In: JBJS case connector, Vol. 8, No. 3, 01.07.2018, p. e74.

Research output: Contribution to journalArticle

Wanderman, NR, Drayer, NJ, Tomov, M, Reifsnyder, JW, Carlson, B, Robinson, W, Kang, DG & Freedman, B 2018, 'Postoperative Seroma Formation After Posterior Cervical Fusion with Use of RhBMP-2: A Report of Two Cases', JBJS case connector, vol. 8, no. 3, pp. e74. https://doi.org/10.2106/JBJS.CC.18.00089
Wanderman, Nathan R. ; Drayer, Nicholas J. ; Tomov, Marko ; Reifsnyder, Jeremy W. ; Carlson, Bayard ; Robinson, William ; Kang, Daniel G. ; Freedman, Brett. / Postoperative Seroma Formation After Posterior Cervical Fusion with Use of RhBMP-2 : A Report of Two Cases. In: JBJS case connector. 2018 ; Vol. 8, No. 3. pp. e74.
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