Postoperative outcome of patients with narcolepsy. A retrospective analysis

Bethanie Burrow, Christopher Burkle, David Oman Warner, Eduardo Nunes Chini

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Study Objective: To determine the postoperative outcome of narcolepsy patients, a population that may be at increased risk of perioperative complications, including postoperative hypersomnia, prolonged emergence after general anesthesia, and apnea. Design: Retrospective chart review. Setting: Academic medical center. Measurements: The perioperative outcome of pharmacologically treated narcolepsy patients, diagnosed at the Mayo Clinic sleep laboratory between January 1, 1965, and December 31, 2001, was studied. A total of 37 narcolepsy patients was identified. Charts were reviewed for the following perioperative (intraoperative time plus recovery room time) events: time for extubation, duration of stay in the Postanesthesia Care Unit (PACU), and duration of stay in the hospital. Furthermore, any of the following complications were noted: electrocardiographic (ECG) changes, postoperative nausea and vomiting, hypotension, subjective reports of pain, decreasing oxygen saturation (SpO2) levels, respiratory complications, postoperative fever, agitation in the PACU, and hypersomnolence in PACU. In addition, patient hospital stay and major morbidity and mortality during hospital stay were recorded. Main Results: Ten patients pharmacologically treated for their narcolepsy symptoms that underwent 27 noncardiac surgical procedures under general anesthesia. We found no evidence that the pharmacologically treated narcolepsy patients were at any increased risk for perioperative complications. Furthermore, their time for endotracheal extubation, length of stay in the PACU and hospital did not differ from nonnarcolepsy patients. Conclusion: Pharmacological therapy for narcolepsy should be continued during the perioperative period. In addition, treated narcolepsy patients are at no increased risk for postoperative complications.

Original languageEnglish (US)
Pages (from-to)21-25
Number of pages5
JournalJournal of Clinical Anesthesia
Volume17
Issue number1
DOIs
StatePublished - Feb 2005

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Narcolepsy
Length of Stay
Disorders of Excessive Somnolence
General Anesthesia
Airway Extubation
Recovery Room
Postoperative Nausea and Vomiting
Perioperative Period
Hospital Units
Apnea
Hypotension
Sleep
Fever
Pharmacology
Oxygen
Morbidity
Pain
Mortality

Keywords

  • Anesthesia
  • Methylphenidate
  • Narcolepsy
  • Sleep disorders
  • Surgery

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Postoperative outcome of patients with narcolepsy. A retrospective analysis. / Burrow, Bethanie; Burkle, Christopher; Warner, David Oman; Chini, Eduardo Nunes.

In: Journal of Clinical Anesthesia, Vol. 17, No. 1, 02.2005, p. 21-25.

Research output: Contribution to journalArticle

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