Postoperative hyperthermia following off-pump versus on-pump coronary artery bypass surgery

Jeffrey A. Clark, Shahar Bar-Yosef, Amanda Anderson, Mark F. Newman, Kevin Landolfo, Hilary P. Grocott

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objective: Hyperthermia is common in the first 24 hours following coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass (CPB). An inflammatory response to CPB is often implicated in the pathophysiology of this fever. Unlike CABG with CPB, the temperature pattern after off-pump CABG (OPCAB), where CPB is avoided, has not yet been described. The purpose of this study was to describe the postoperative temperature pattern following OPCAB and to compare it with that following on-pump cardiac surgery. Design: Retrospective, observational study. Setting: Tertiary care university hospital. Participants: Consenting patients undergoing CABG or OPCAB procedures. Interventions: Observational. Measurements and Main Results: Of the CABG patients, 89% had temperature elevations above 38°C, versus 44% of the OPCAB patients (P = 0.04). Peak body temperature was higher in the on-pump patients (CABG 38.5°C ± 0.4°C versus OPCAB 37.9°C ± 0.5°C; P = 0.002), as was the area under the curve for temperatures greater than 38°C (CABG 1.6 ± 1.7°C/hr versus OPCAB 0.4 ± 1.2°C/hr; P = 0.02). Conclusions: Off-pump CABG surgery patients experience less hyperthermia compared with on-pump CABG patients. The reasons for a lower incidence and severity of hyperthermia after OPCAB surgery are not known, but may be related to a reduced inflammatory response.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalJournal of Cardiothoracic and Vascular Anesthesia
Volume19
Issue number4
DOIs
StatePublished - Aug 2005
Externally publishedYes

Fingerprint

Coronary Artery Bypass
Fever
Transplants
Cardiopulmonary Bypass
Off-Pump Coronary Artery Bypass
Temperature
Tertiary Healthcare
Body Temperature
Thoracic Surgery
Area Under Curve
Observational Studies
Retrospective Studies
Incidence

Keywords

  • Coronary artery bypass surgery
  • Hyperthermia
  • Off-pump coronary artery bypass

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Postoperative hyperthermia following off-pump versus on-pump coronary artery bypass surgery. / Clark, Jeffrey A.; Bar-Yosef, Shahar; Anderson, Amanda; Newman, Mark F.; Landolfo, Kevin; Grocott, Hilary P.

In: Journal of Cardiothoracic and Vascular Anesthesia, Vol. 19, No. 4, 08.2005, p. 426-429.

Research output: Contribution to journalArticle

Clark, Jeffrey A. ; Bar-Yosef, Shahar ; Anderson, Amanda ; Newman, Mark F. ; Landolfo, Kevin ; Grocott, Hilary P. / Postoperative hyperthermia following off-pump versus on-pump coronary artery bypass surgery. In: Journal of Cardiothoracic and Vascular Anesthesia. 2005 ; Vol. 19, No. 4. pp. 426-429.
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