TY - JOUR
T1 - Posterior pole and peripheral retinal fibrovascular proliferation in von hippel-lindau disease
AU - Elborgy, Ebrahim
AU - Pulido, Jose S
PY - 2017
Y1 - 2017
N2 - Purpose: To report the occurrence of fibrovascular proliferation (FVP) in the retina in von Hippel-Lindau (VHL) patients and its association with prior treatment. Design: Aretrospective study.Methods: Aretrospective study of 101 VHLpatients. Fundus photos were available for 28 patients. FVP was classified into peripheral and posterior pole. Results: All 28 patients had retinal capillary hemangioblastomas (RCH) in 1 or both eyes; 15 patients were found to have FVP (group A), whereas 13 patients did not (group B). Mean age of patients in group Awas 35 ± 11.3 years and 36.6 ± 13.8 in group B (P = 0.74). In group A, 27 eyes had RCH; 21 (77.77%) had FVP. In group B, 19 eyes had RCH. The number of treated eyes was significantly higher in group A(81.48%) than group B (42.1%) (P = 0.007). In group A, FVP was noted in the posterior pole in 9 eyes, in the periphery in 5 eyes, and 7 eyes developed both posterior pole and peripheral FVP. Conclusions: FVP can occur in the peripheral retina and in the posterior pole. There is a significant association between prior treatment of RCH and the occurrence of FVP.
AB - Purpose: To report the occurrence of fibrovascular proliferation (FVP) in the retina in von Hippel-Lindau (VHL) patients and its association with prior treatment. Design: Aretrospective study.Methods: Aretrospective study of 101 VHLpatients. Fundus photos were available for 28 patients. FVP was classified into peripheral and posterior pole. Results: All 28 patients had retinal capillary hemangioblastomas (RCH) in 1 or both eyes; 15 patients were found to have FVP (group A), whereas 13 patients did not (group B). Mean age of patients in group Awas 35 ± 11.3 years and 36.6 ± 13.8 in group B (P = 0.74). In group A, 27 eyes had RCH; 21 (77.77%) had FVP. In group B, 19 eyes had RCH. The number of treated eyes was significantly higher in group A(81.48%) than group B (42.1%) (P = 0.007). In group A, FVP was noted in the posterior pole in 9 eyes, in the periphery in 5 eyes, and 7 eyes developed both posterior pole and peripheral FVP. Conclusions: FVP can occur in the peripheral retina and in the posterior pole. There is a significant association between prior treatment of RCH and the occurrence of FVP.
KW - fibrovascular proliferation
KW - Retina
KW - Retinal capillary hemangioblastoma
KW - Retinal neovascularization
KW - Von Hippel-Lindau disease
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U2 - 10.22608/APO.2016205
DO - 10.22608/APO.2016205
M3 - Article
C2 - 28558182
AN - SCOPUS:85020185725
VL - 6
SP - 256
EP - 260
JO - Asia-Pacific Journal of Ophthalmology
JF - Asia-Pacific Journal of Ophthalmology
SN - 2162-0989
IS - 3
ER -