Posterior pole and peripheral retinal fibrovascular proliferation in von hippel-lindau disease

Ebrahim Elborgy, Jose S Pulido

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: To report the occurrence of fibrovascular proliferation (FVP) in the retina in von Hippel-Lindau (VHL) patients and its association with prior treatment. Design: Aretrospective study.Methods: Aretrospective study of 101 VHLpatients. Fundus photos were available for 28 patients. FVP was classified into peripheral and posterior pole. Results: All 28 patients had retinal capillary hemangioblastomas (RCH) in 1 or both eyes; 15 patients were found to have FVP (group A), whereas 13 patients did not (group B). Mean age of patients in group Awas 35 ± 11.3 years and 36.6 ± 13.8 in group B (P = 0.74). In group A, 27 eyes had RCH; 21 (77.77%) had FVP. In group B, 19 eyes had RCH. The number of treated eyes was significantly higher in group A(81.48%) than group B (42.1%) (P = 0.007). In group A, FVP was noted in the posterior pole in 9 eyes, in the periphery in 5 eyes, and 7 eyes developed both posterior pole and peripheral FVP. Conclusions: FVP can occur in the peripheral retina and in the posterior pole. There is a significant association between prior treatment of RCH and the occurrence of FVP.

Original languageEnglish (US)
Pages (from-to)256-260
Number of pages5
JournalAsia-Pacific Journal of Ophthalmology
Volume6
Issue number3
DOIs
StatePublished - 2017

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von Hippel-Lindau Disease
Hemangioblastoma
Retina
Therapeutics

Keywords

  • fibrovascular proliferation
  • Retina
  • Retinal capillary hemangioblastoma
  • Retinal neovascularization
  • Von Hippel-Lindau disease

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Posterior pole and peripheral retinal fibrovascular proliferation in von hippel-lindau disease. / Elborgy, Ebrahim; Pulido, Jose S.

In: Asia-Pacific Journal of Ophthalmology, Vol. 6, No. 3, 2017, p. 256-260.

Research output: Contribution to journalArticle

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abstract = "Purpose: To report the occurrence of fibrovascular proliferation (FVP) in the retina in von Hippel-Lindau (VHL) patients and its association with prior treatment. Design: Aretrospective study.Methods: Aretrospective study of 101 VHLpatients. Fundus photos were available for 28 patients. FVP was classified into peripheral and posterior pole. Results: All 28 patients had retinal capillary hemangioblastomas (RCH) in 1 or both eyes; 15 patients were found to have FVP (group A), whereas 13 patients did not (group B). Mean age of patients in group Awas 35 ± 11.3 years and 36.6 ± 13.8 in group B (P = 0.74). In group A, 27 eyes had RCH; 21 (77.77{\%}) had FVP. In group B, 19 eyes had RCH. The number of treated eyes was significantly higher in group A(81.48{\%}) than group B (42.1{\%}) (P = 0.007). In group A, FVP was noted in the posterior pole in 9 eyes, in the periphery in 5 eyes, and 7 eyes developed both posterior pole and peripheral FVP. Conclusions: FVP can occur in the peripheral retina and in the posterior pole. There is a significant association between prior treatment of RCH and the occurrence of FVP.",
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