Polyneuropathy in hypereosinophilic syndrome

S. Monaco, B. Lucci, N. Laperchia, F. Tezzon, B. Curro-Dossi, E. Nardelli, Caterina Giannini, N. Rizzuto

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

We investigated two patients with the idiopathic hypereosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy. Morphologic changes of the nerve biopsies suggested axonal damage secondary to increased endoneurial pressure from leakage of capillaries. We postulated that endothelial cell damage, followed by nerve edema, is the first step in the pathogenesis of peripheral neuropathy in these patients.

Original languageEnglish (US)
Pages (from-to)494-496
Number of pages3
JournalNeurology
Volume38
Issue number3
StatePublished - 1988
Externally publishedYes

Fingerprint

Hypereosinophilic Syndrome
Polyneuropathies
Peripheral Nervous System Diseases
Edema
Endothelial Cells
Biopsy
Pressure

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Monaco, S., Lucci, B., Laperchia, N., Tezzon, F., Curro-Dossi, B., Nardelli, E., ... Rizzuto, N. (1988). Polyneuropathy in hypereosinophilic syndrome. Neurology, 38(3), 494-496.

Polyneuropathy in hypereosinophilic syndrome. / Monaco, S.; Lucci, B.; Laperchia, N.; Tezzon, F.; Curro-Dossi, B.; Nardelli, E.; Giannini, Caterina; Rizzuto, N.

In: Neurology, Vol. 38, No. 3, 1988, p. 494-496.

Research output: Contribution to journalArticle

Monaco, S, Lucci, B, Laperchia, N, Tezzon, F, Curro-Dossi, B, Nardelli, E, Giannini, C & Rizzuto, N 1988, 'Polyneuropathy in hypereosinophilic syndrome', Neurology, vol. 38, no. 3, pp. 494-496.
Monaco S, Lucci B, Laperchia N, Tezzon F, Curro-Dossi B, Nardelli E et al. Polyneuropathy in hypereosinophilic syndrome. Neurology. 1988;38(3):494-496.
Monaco, S. ; Lucci, B. ; Laperchia, N. ; Tezzon, F. ; Curro-Dossi, B. ; Nardelli, E. ; Giannini, Caterina ; Rizzuto, N. / Polyneuropathy in hypereosinophilic syndrome. In: Neurology. 1988 ; Vol. 38, No. 3. pp. 494-496.
@article{b1ddd488c2194acbac3e575f59df3c06,
title = "Polyneuropathy in hypereosinophilic syndrome",
abstract = "We investigated two patients with the idiopathic hypereosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy. Morphologic changes of the nerve biopsies suggested axonal damage secondary to increased endoneurial pressure from leakage of capillaries. We postulated that endothelial cell damage, followed by nerve edema, is the first step in the pathogenesis of peripheral neuropathy in these patients.",
author = "S. Monaco and B. Lucci and N. Laperchia and F. Tezzon and B. Curro-Dossi and E. Nardelli and Caterina Giannini and N. Rizzuto",
year = "1988",
language = "English (US)",
volume = "38",
pages = "494--496",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Polyneuropathy in hypereosinophilic syndrome

AU - Monaco, S.

AU - Lucci, B.

AU - Laperchia, N.

AU - Tezzon, F.

AU - Curro-Dossi, B.

AU - Nardelli, E.

AU - Giannini, Caterina

AU - Rizzuto, N.

PY - 1988

Y1 - 1988

N2 - We investigated two patients with the idiopathic hypereosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy. Morphologic changes of the nerve biopsies suggested axonal damage secondary to increased endoneurial pressure from leakage of capillaries. We postulated that endothelial cell damage, followed by nerve edema, is the first step in the pathogenesis of peripheral neuropathy in these patients.

AB - We investigated two patients with the idiopathic hypereosinophilic syndrome and peripheral neuropathy. Clinical, EMG, and pathological findings were consistent with axonal polyneuropathy. Morphologic changes of the nerve biopsies suggested axonal damage secondary to increased endoneurial pressure from leakage of capillaries. We postulated that endothelial cell damage, followed by nerve edema, is the first step in the pathogenesis of peripheral neuropathy in these patients.

UR - http://www.scopus.com/inward/record.url?scp=0023854857&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023854857&partnerID=8YFLogxK

M3 - Article

C2 - 2831471

AN - SCOPUS:0023854857

VL - 38

SP - 494

EP - 496

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 3

ER -