Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 (PSPLA1)

Jian Wang, Xiao Yan Wen, Alexander Keith Stewart, Robert A. Hegele

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We report the identification of nine DNA polymorphisms in PSPLA1 encoding phosphatidylserinespecific phospholipase A1. Because the gene product shares homology with triglyceride lipases, these polymorphisms may be useful in association studies with metabolic traits such as hypertriglyceridemia and related lipoprotein abnormalities, and will also provide tools for mapping studies of chromosome 3q13.13-13.2.

Original languageEnglish (US)
Pages (from-to)611-613
Number of pages3
JournalJournal of Human Genetics
Volume47
Issue number11
StatePublished - 2002
Externally publishedYes

Fingerprint

Phospholipases A1
Phosphatidylserines
Hypertriglyceridemia
Chromosome Mapping
Lipase
Genes
Lipoproteins
DNA

Keywords

  • Complex traits
  • Genomic DNA
  • Lipase
  • Metabolism
  • Sequencing
  • Triglyceride

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 (PSPLA1). / Wang, Jian; Wen, Xiao Yan; Stewart, Alexander Keith; Hegele, Robert A.

In: Journal of Human Genetics, Vol. 47, No. 11, 2002, p. 611-613.

Research output: Contribution to journalArticle

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